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T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.
Céspedes PF, Jainarayanan A, Fernández-Messina L, Valvo S, Saliba DG, Kurz E, Kvalvaag A, Chen L, Ganskow C, Colin-York H, Fritzsche M, Peng Y, Dong T, Johnson E, Siller-Farfán JA, Dushek O, Sezgin E, Peacock B, Law A, Aubert D, Engledow S, Attar M, Hester S, Fischer R, Sánchez-Madrid F, Dustin ML. Céspedes PF, et al. Among authors: kurz e. Nat Commun. 2022 Jun 16;13(1):3460. doi: 10.1038/s41467-022-31160-3. Nat Commun. 2022. PMID: 35710644 Free PMC article.
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens.
Hellmeier J, Platzer R, Eklund AS, Schlichthaerle T, Karner A, Motsch V, Schneider MC, Kurz E, Bamieh V, Brameshuber M, Preiner J, Jungmann R, Stockinger H, Schütz GJ, Huppa JB, Sevcsik E. Hellmeier J, et al. Among authors: kurz e. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2016857118. doi: 10.1073/pnas.2016857118. Proc Natl Acad Sci U S A. 2021. PMID: 33468643 Free PMC article.
Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer.
Sivakumar S, Abu-Shah E, Ahern DJ, Arbe-Barnes EH, Jainarayanan AK, Mangal N, Reddy S, Rendek A, Easton A, Kurz E, Silva M, Soonawalla Z, Heij LR, Bashford-Rogers R, Middleton MR, Dustin ML. Sivakumar S, et al. Among authors: kurz e. Cancers (Basel). 2021 Apr 8;13(8):1776. doi: 10.3390/cancers13081776. Cancers (Basel). 2021. PMID: 33917832 Free PMC article.
Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells.
Kirstetter P, Schuster MB, Bereshchenko O, Moore S, Dvinge H, Kurz E, Theilgaard-Mönch K, Månsson R, Pedersen TA, Pabst T, Schrock E, Porse BT, Jacobsen SE, Bertone P, Tenen DG, Nerlov C. Kirstetter P, et al. Among authors: kurz e. Cancer Cell. 2008 Apr;13(4):299-310. doi: 10.1016/j.ccr.2008.02.008. Cancer Cell. 2008. PMID: 18394553 Free article.