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2011 2
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29 results

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Page 1
Oligomeric α-synuclein and tau aggregates in NDEVs differentiate Parkinson's disease from atypical parkinsonisms.
Meloni M, Agliardi C, Guerini FR, Zanzottera M, Bolognesi E, Picciolini S, Marano M, Magliozzi A, Di Fonzo A, Arighi A, Fenoglio C, Franco G, Arienti F, Saibene FL, Navarro J, Clerici M. Meloni M, et al. Neurobiol Dis. 2023 Jan;176:105947. doi: 10.1016/j.nbd.2022.105947. Epub 2022 Dec 5. Neurobiol Dis. 2023. PMID: 36481435 Free article.
NDEVs were isolated from serum by immunocapture using an antibody against the neuronal surface marker L1CAM; oligomeric alpha-Synuclein and aggregated Tau were measured by ELISA. NDEVs analyses showed that oligomeric alpha-Synuclein is significantly augmented in PD compare …
NDEVs were isolated from serum by immunocapture using an antibody against the neuronal surface marker L1CAM; oligomeric alpha-Synuclein and …
Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study.
van der Ende EL, Heller C, Sogorb-Esteve A, Swift IJ, McFall D, Peakman G, Bouzigues A, Poos JM, Jiskoot LC, Panman JL, Papma JM, Meeter LH, Dopper EGP, Bocchetta M, Todd E, Cash D, Graff C, Synofzik M, Moreno F, Finger E, Sanchez-Valle R, Vandenberghe R, Laforce R Jr, Masellis M, Tartaglia MC, Rowe JB, Butler C, Ducharme S, Gerhard A, Danek A, Levin J, Pijnenburg YAL, Otto M, Borroni B, Tagliavini F, de Mendonça A, Santana I, Galimberti D, Sorbi S, Zetterberg H, Huang E, van Swieten JC, Rohrer JD, Seelaar H; Genetic Frontotemporal Dementia Initiative (GENFI). van der Ende EL, et al. J Neuroinflammation. 2022 Sep 5;19(1):217. doi: 10.1186/s12974-022-02573-0. J Neuroinflammation. 2022. PMID: 36064709 Free PMC article.
METHODS: We measured the complement proteins C1q and C3b in CSF by ELISAs in 224 presymptomatic and symptomatic GRN, C9orf72 or MAPT mutation carriers and non-carriers participating in the Genetic Frontotemporal Dementia Initiative (GENFI), a multicentre cohort study. ...
METHODS: We measured the complement proteins C1q and C3b in CSF by ELISAs in 224 presymptomatic and symptomatic GRN, C9orf72 or MAPT …
Exploring Links Between Psychosis and Frontotemporal Dementia Using Multimodal Machine Learning: Dementia Praecox Revisited.
Koutsouleris N, Pantelis C, Velakoulis D, McGuire P, Dwyer DB, Urquijo-Castro MF, Paul R, Dong S, Popovic D, Oeztuerk O, Kambeitz J, Salokangas RKR, Hietala J, Bertolino A, Brambilla P, Upthegrove R, Wood SJ, Lencer R, Borgwardt S, Maj C, Nöthen M, Degenhardt F, Polyakova M, Mueller K, Villringer A, Danek A, Fassbender K, Fliessbach K, Jahn H, Kornhuber J, Landwehrmeyer B, Anderl-Straub S, Prudlo J, Synofzik M, Wiltfang J, Riedl L, Diehl-Schmid J, Otto M, Meisenzahl E, Falkai P, Schroeter ML; International FTD-Genetics Consortium (IFGC), the German Frontotemporal Lobar Degeneration (FTLD) Consortium, and the PRONIA Consortium. Koutsouleris N, et al. JAMA Psychiatry. 2022 Sep 1;79(9):907-919. doi: 10.1001/jamapsychiatry.2022.2075. JAMA Psychiatry. 2022. PMID: 35921104 Free PMC article.
Evidence of alterations of Beta-endorphin levels and Mu-opioid receptor gene expression in bipolar disorder.
Escelsior A, Sterlini B, Tardito S, Altosole T, Magioncalda P, Martino M, Serafini G, Murri MB, Aguglia A, Amerio A, da Silva BP, Trabucco A, Fenoglio D, Filaci G, Amore M. Escelsior A, et al. Psychiatry Res. 2022 Oct;316:114787. doi: 10.1016/j.psychres.2022.114787. Epub 2022 Aug 11. Psychiatry Res. 2022. PMID: 35988328
Plasma levels of beta-END and MOR gene expression in peripheral blood mononuclear cells were analyzed using ELISA Immunoassay qRT-PCR. We found that subjects with BD exhibited a significant upregulation of MOR gene expression and a decrease of beta-END (p<0.0001 for bot …
Plasma levels of beta-END and MOR gene expression in peripheral blood mononuclear cells were analyzed using ELISA Immunoassay qRT-PCR …
A Novel Automated Chemiluminescence Method for Detecting Cerebrospinal Fluid Amyloid-Beta 1-42 and 1-40, Total Tau and Phosphorylated-Tau: Implications for Improving Diagnostic Performance in Alzheimer's Disease.
Arcaro M, Fenoglio C, Serpente M, Arighi A, Fumagalli GG, Sacchi L, Floro S, D'Anca M, Sorrentino F, Visconte C, Perego A, Scarpini E, Galimberti D. Arcaro M, et al. Biomedicines. 2022 Oct 21;10(10):2667. doi: 10.3390/biomedicines10102667. Biomedicines. 2022. PMID: 36289929 Free PMC article.

Results confirmed a robust correlation between ELISA and CLEIA methods, with an improvement of the accuracy with the new CLEIA methodology in the detection of the single biomarkers and in their ratio values. ...AUC CLEIA = 0.95 (95% CI 0.89; 1.00 p < 0.0001), and P-tau1

Results confirmed a robust correlation between ELISA and CLEIA methods, with an improvement of the accuracy with the new CLEIA method …
Modulation of MAPK- and PI3/AKT-Dependent Autophagy Signaling by Stavudine (D4T) in PBMC of Alzheimer's Disease Patients.
La Rosa F, Zoia CP, Bazzini C, Bolognini A, Saresella M, Conti E, Ferrarese C, Piancone F, Marventano I, Galimberti D, Fenoglio C, Scarpini E, Clerici M. La Rosa F, et al. Cells. 2022 Jul 12;11(14):2180. doi: 10.3390/cells11142180. Cells. 2022. PMID: 35883623 Free PMC article.
We analyzed the NLRP3 activity by measuring NLRP3-ASC complex formation by AMNIS FlowSight and pro-inflammatory cytokine (IL-1beta, IL-18 and Caspase-1) production by ELISA. The phosphorylation status of p38, ERK, AKT, p70, and the protein expression of CREB, LAMP2A, becli …
We analyzed the NLRP3 activity by measuring NLRP3-ASC complex formation by AMNIS FlowSight and pro-inflammatory cytokine (IL-1beta, IL-18 an …
Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer's Disease.
La Rosa F, Mancuso R, Agostini S, Piancone F, Marventano I, Saresella M, Hernis A, Fenoglio C, Galimberti D, Scarpini E, Clerici M. La Rosa F, et al. Pharmaceuticals (Basel). 2021 Nov 20;14(11):1187. doi: 10.3390/ph14111187. Pharmaceuticals (Basel). 2021. PMID: 34832969 Free PMC article.
Expression of genes within the inflammasome complex and of miRNAs was evaluated by RT-PCR; cytokines and caspase-1 production was measured by ELISA. Results have shown that: NLRP3, ASC, IL-1beta and IL-18 expression, as well as IL-18, IL-1beta and caspase-1 production, wer …
Expression of genes within the inflammasome complex and of miRNAs was evaluated by RT-PCR; cytokines and caspase-1 production was measured b …
New insights into immune mechanisms underlying response to Rituximab in patients with membranous nephropathy: A prospective study and a review of the literature.
Roccatello D, Sciascia S, Di Simone D, Solfietti L, Naretto C, Fenoglio R, Baldovino S, Menegatti E. Roccatello D, et al. Autoimmun Rev. 2016 Jun;15(6):529-38. doi: 10.1016/j.autrev.2016.02.014. Epub 2016 Feb 11. Autoimmun Rev. 2016. PMID: 26876383 Review.
Changes in circulating B and T cell homeostasis were examined in the peripheral blood by flow-cytometry studies; serum levels of IL-35 were measured using a high-sensitivity ELISA kits (baseline, at month 3, 6, 9 and 12). RESULTS: Patients had been followed-up for a mean o …
Changes in circulating B and T cell homeostasis were examined in the peripheral blood by flow-cytometry studies; serum levels of IL-35 were …
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid.
Ragheb S, Li Y, Simon K, VanHaerents S, Galimberti D, De Riz M, Fenoglio C, Scarpini E, Lisak R. Ragheb S, et al. Mult Scler. 2011 Jul;17(7):819-29. doi: 10.1177/1352458511398887. Epub 2011 Mar 3. Mult Scler. 2011. PMID: 21372118
OBJECTIVE: To measure BAFF and CXCL13 levels in the cerebrospinal fluid (CSF) of patients with MS compared to patients with other neurological diseases. METHODS: Cytokine/chemokine levels were measured by an enzyme-linked immunosorbent assay (ELISA
OBJECTIVE: To measure BAFF and CXCL13 levels in the cerebrospinal fluid (CSF) of patients with MS compared to patients with other neurologic …
29 results