Hippo pathway dysregulation in gastric cancer: from Helicobacter pylori infection to tumor promotion and progression.
Messina B, Lo Sardo F, Scalera S, Memeo L, Colarossi C, Mare M, Blandino G, Ciliberto G, Maugeri-Saccà M, Bon G.
Messina B, et al.
Cell Death Dis. 2023 Jan 12;14(1):21. doi: 10.1038/s41419-023-05568-8.
Cell Death Dis. 2023.
PMID: 36635265
Free PMC article.
Review.
The Hippo pathway plays a critical role for balancing proliferation and differentiation, thus regulating tissue homeostasis. The pathway acts through a kinase cascade whose final effectors are the Yes-associated protein (YAP) and its paralog transcriptional co-activator wi …
The Hippo pathway plays a critical role for balancing proliferation and differentiation, thus regulating tissue homeostasis. The pathway act …