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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1952 1
1953 2
1954 1
1955 1
1957 1
1963 5
1964 6
1966 1
1967 2
1969 4
1970 4
1971 3
1972 5
1974 1
1975 1
1976 4
1977 6
1978 3
1979 4
1980 2
1981 1
1982 7
1983 6
1984 11
1985 14
1986 5
1987 23
1988 23
1989 12
1990 21
1991 9
1992 31
1993 29
1994 28
1995 21
1996 26
1997 23
1998 27
1999 15
2000 24
2001 27
2002 23
2003 37
2004 33
2005 22
2006 33
2007 35
2008 46
2009 45
2010 34
2011 49
2012 49
2013 56
2014 66
2015 81
2016 103
2017 118
2018 127
2019 138
2020 179
2021 196
2022 214
2023 225
2024 77

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2,167 results

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The following term was not found in PubMed: Liberman-Pincu
Page 1
Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway.
Chen D, Yu W, Zhong C, Hong Q, Huang G, Que D, Wang Y, Yang Y, Rui B, Zhuang Z, Liang M, Ye Z, Yan X, Lv J, Zhang R, Yan J, Yang P. Chen D, et al. Pharmacol Res. 2022 Apr;178:106186. doi: 10.1016/j.phrs.2022.106186. Epub 2022 Mar 17. Pharmacol Res. 2022. PMID: 35306141
Chloroquine, a classical autophagic flux inhibitor, blunted the improvement of ELA on cardiac dysfunction. At last, we revealed that ELA reversed DOX-induced downregulation of transcription factor EB (TFEB), and silencing TFEB by siRNA abrogated the effects of EL …
Chloroquine, a classical autophagic flux inhibitor, blunted the improvement of ELA on cardiac dysfunction. At last, we revealed that …
Elabela-APJ axis mediates angiogenesis via YAP/TAZ pathway in cerebral ischemia/reperfusion injury.
Li W, Xu P, Kong L, Feng S, Shen N, Huang H, Wang W, Xu X, Wang X, Wang G, Zhang Y, Sun W, Hu W, Liu X. Li W, et al. Transl Res. 2023 Jul;257:78-92. doi: 10.1016/j.trsl.2023.02.002. Epub 2023 Feb 21. Transl Res. 2023. PMID: 36813109
We aimed to investigate the function of endothelial ELA on post-ischemic cerebral angiogenesis. Here, we demonstrated that the endothelial ELA expression was upregulated in the ischemic brain and treatment with ELA-32 mitigated brain injury and enhanced the r …
We aimed to investigate the function of endothelial ELA on post-ischemic cerebral angiogenesis. Here, we demonstrated that the endoth …
Stress-induced plasticity of a CRH/GABA projection disrupts reward behaviors in mice.
Birnie MT, Short AK, de Carvalho GB, Taniguchi L, Gunn BG, Pham AL, Itoga CA, Xu X, Chen LY, Mahler SV, Chen Y, Baram TZ. Birnie MT, et al. Nat Commun. 2023 Feb 25;14(1):1088. doi: 10.1038/s41467-023-36780-x. Nat Commun. 2023. PMID: 36841826 Free PMC article.
Disrupted operations of the reward circuit underlie major emotional disorders, including depression, which commonly arise following early life stress / adversity (ELA). However, how ELA enduringly impacts reward circuit functions remains unclear. ...In adult ELA …
Disrupted operations of the reward circuit underlie major emotional disorders, including depression, which commonly arise following early li …
Early life adversity as a risk factor for cognitive impairment and Alzheimer's disease.
Huang Z, Jordan JD, Zhang Q. Huang Z, et al. Transl Neurodegener. 2023 May 12;12(1):25. doi: 10.1186/s40035-023-00355-z. Transl Neurodegener. 2023. PMID: 37173751 Free PMC article. Review.
In rodent models, exposure to ELA results in specific cognitive deficits and aggravated AD pathology. ...Additionally, we discuss several interventions that may alleviate adverse consequences of ELA. Further investigation into this crucial area will help improve …
In rodent models, exposure to ELA results in specific cognitive deficits and aggravated AD pathology. ...Additionally, we discuss sev …
Elabela-APJ axis attenuates cerebral ischemia/reperfusion injury by inhibiting neuronal ferroptosis.
Xu P, Kong L, Tao C, Zhu Y, Cheng J, Li W, Shen N, Li R, Zhang C, Wang L, Zhang Y, Wang G, Liu X, Sun W, Hu W. Xu P, et al. Free Radic Biol Med. 2023 Feb 20;196:171-186. doi: 10.1016/j.freeradbiomed.2023.01.008. Epub 2023 Jan 18. Free Radic Biol Med. 2023. PMID: 36681202
The present study showed that ELA and APJ were expressed on neurons and increased after cerebral I/R injury. ...Together, these findings suggested that ELA-APJ axis mitigates neuronal ferroptosis after ischemic stroke and that the ELA-32 peptide may be a puta …
The present study showed that ELA and APJ were expressed on neurons and increased after cerebral I/R injury. ...Together, these findi …
ELABELA/APJ Axis Prevents Diabetic Glomerular Endothelial Injury by Regulating AMPK/NLRP3 Pathway.
Chen Z, Wang Z, Hu Y, Lin H, Yin L, Kong J, Zhang Y, Hu B, Li T, Zheng X, Yang Q, Ye S, Wang S, Zhou Q, Zheng C. Chen Z, et al. Inflammation. 2023 Dec;46(6):2343-2358. doi: 10.1007/s10753-023-01882-7. Epub 2023 Aug 4. Inflammation. 2023. PMID: 37540330 Free PMC article.
ELABELA (ELA), a recently discovered peptide, is highly expressed in adult kidneys and the endothelium system. ...It was also found that ELA deficiency in ELA(+/-) mice significantly accelerated diabetic glomerular injury, as shown by exacerbated glomerular m …
ELABELA (ELA), a recently discovered peptide, is highly expressed in adult kidneys and the endothelium system. ...It was also found t …
Early life adversity across different cell- types in the brain.
Warhaftig G, Almeida D, Turecki G. Warhaftig G, et al. Neurosci Biobehav Rev. 2023 May;148:105113. doi: 10.1016/j.neubiorev.2023.105113. Epub 2023 Feb 28. Neurosci Biobehav Rev. 2023. PMID: 36863603 Review.
As ELA has a lasting impact on the brain at a developmental stage, recent findings from the field highlighted the specific contributions of different cell types to ELA and their association with long lasting consequences. ...The findings reviewed and summarized here …
As ELA has a lasting impact on the brain at a developmental stage, recent findings from the field highlighted the specific contributi …
Early life adversity shapes neural circuit function during sensitive postnatal developmental periods.
Malave L, van Dijk MT, Anacker C. Malave L, et al. Transl Psychiatry. 2022 Aug 1;12(1):306. doi: 10.1038/s41398-022-02092-9. Transl Psychiatry. 2022. PMID: 35915071 Free PMC article. Review.
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological mechanisms by which ELA increases the risk for future psychopathology are still poorly understood. ...We also discuss how gene-by-environment (GxE) interactions can determi …
Early life adversity (ELA) is a major risk factor for mental illness, but the neurobiological mechanisms by which ELA increase …
A promising therapeutic peptide and preventive/diagnostic biomarker for age-related diseases: The Elabela/Apela/Toddler peptide.
Monastero R, Magro D, Venezia M, Pisano C, Balistreri CR. Monastero R, et al. Ageing Res Rev. 2023 Nov;91:102076. doi: 10.1016/j.arr.2023.102076. Epub 2023 Sep 29. Ageing Res Rev. 2023. PMID: 37776977 Free article. Review.
Elabela (ELA), Apela or Toddler peptide is a hormone peptide belonging to the adipokine group and a component of apelinergic system, discovered in 2013-2014. Given its high homology with apelin, the first ligand of APJ receptor, ELA likely mediates similar effects. …
Elabela (ELA), Apela or Toddler peptide is a hormone peptide belonging to the adipokine group and a component of apelinergic system, …
Therapeutic potential of apelin and Elabela in cardiovascular disease.
Gao S, Chen H. Gao S, et al. Biomed Pharmacother. 2023 Oct;166:115268. doi: 10.1016/j.biopha.2023.115268. Epub 2023 Aug 8. Biomed Pharmacother. 2023. PMID: 37562237 Free article. Review.
Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively, which act on their receptor APJ and play crucial roles in the body. ...Evidences indicated that apelin and Ela play important roles in cardiovascular diseases, and there are many studies …
Apelin and Elabela (Ela) are peptides encoded by APLN and APELA, respectively, which act on their receptor APJ and play crucial roles …
2,167 results