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Page 1
Therapeutic Implications of Germline Testing in Patients With Advanced Cancers.
Stadler ZK, Maio A, Chakravarty D, Kemel Y, Sheehan M, Salo-Mullen E, Tkachuk K, Fong CJ, Nguyen B, Erakky A, Cadoo K, Liu Y, Carlo MI, Latham A, Zhang H, Kundra R, Smith S, Galle J, Aghajanian C, Abu-Rustum N, Varghese A, O'Reilly EM, Morris M, Abida W, Walsh M, Drilon A, Jayakumaran G, Zehir A, Ladanyi M, Ceyhan-Birsoy O, Solit DB, Schultz N, Berger MF, Mandelker D, Diaz LA Jr, Offit K, Robson ME. Stadler ZK, et al. J Clin Oncol. 2021 Aug 20;39(24):2698-2709. doi: 10.1200/JCO.20.03661. Epub 2021 Jun 16. J Clin Oncol. 2021. PMID: 34133209 Free PMC article.
Of BRCA1/2 patients receiving a poly(ADP-ribose) polymerase inhibitor, 45% (84 of 188) had tumors other than breast or ovarian cancer, wherein the drug, at time of delivery, was delivered in an investigational setting. CONCLUSION: In a pan-cancer analysis, 8% of patients w …
Of BRCA1/2 patients receiving a poly(ADP-ribose) polymerase inhibitor, 45% (84 of 188) had tumors other than breast or ovarian cancer, where …
The gene expression profile and cell of origin of canine peripheral T-cell lymphoma.
Owens E, Harris L, Harris A, Yoshimoto J, Burnett R, Avery A. Owens E, et al. BMC Cancer. 2024 Jan 2;24(1):18. doi: 10.1186/s12885-023-11762-w. BMC Cancer. 2024. PMID: 38166662 Free PMC article.
We utilized gene set variation analysis to evaluate individual canine CD4+ PTCLs for various human and murine T-cell and thymocyte gene signatures. Cultured canine PTCL cells were treated with a pan-PI3K inhibitor, and cell survival and proliferation were compared to DMSO- …
We utilized gene set variation analysis to evaluate individual canine CD4+ PTCLs for various human and murine T-cell and thymocyte gene sign …
Analysis of the National Adult Nutrition Survey (Ireland) and the Food4Me Nutrition Survey Databases to Explore the Development of Food Labelling Portion Sizes for the European Union.
Gibney MJ, O'Sullivan A, Flynn A, Walton J, Daniel H, Manios Y, Martinez A, Saris WHM, Gibney ER, Uzhova I. Gibney MJ, et al. Nutrients. 2018 Dec 20;11(1):6. doi: 10.3390/nu11010006. Nutrients. 2018. PMID: 30577456 Free PMC article.
The surveys were selected as they differed in (a) methodologies (food diary versus food frequency questionnaire), (b) populations (Irish National Adult Nutrition Survey (NANS) versus a seven-country survey based on the pan EU study Food4Me), (c) food quantification (multip …
The surveys were selected as they differed in (a) methodologies (food diary versus food frequency questionnaire), (b) populations (Irish Nat …