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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 3
2003 5
2004 4
2005 1
2006 4
2007 9
2008 9
2009 6
2010 4
2011 5
2012 11
2013 6
2014 6
2015 11
2016 7
2017 5
2018 9
2019 6
2020 9
2021 5
2022 4
2023 5
2024 3

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129 results

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Page 1
An antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, De Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin AMJJ, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: breukink e. Cell. 2023 Sep 14;186(19):4059-4073.e27. doi: 10.1016/j.cell.2023.07.038. Epub 2023 Aug 22. Cell. 2023. PMID: 37611581 Free article.
Teixobactin kills bacteria by a two-pronged attack on the cell envelope.
Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M. Shukla R, et al. Among authors: breukink e. Nature. 2022 Aug;608(7922):390-396. doi: 10.1038/s41586-022-05019-y. Epub 2022 Aug 3. Nature. 2022. PMID: 35922513 Free PMC article.
Non-lipid II targeting lantibiotics.
Wang X, Gu Q, Breukink E. Wang X, et al. Among authors: breukink e. Biochim Biophys Acta Biomembr. 2020 Aug 1;1862(8):183244. doi: 10.1016/j.bbamem.2020.183244. Epub 2020 Feb 29. Biochim Biophys Acta Biomembr. 2020. PMID: 32126235 Free article. Review. No abstract available.
A new antibiotic from an uncultured bacterium binds to an immutable target.
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Lavore F, Honorato RV, Grein F, Bonvin A, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwalen CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, Weingarth M. Shukla R, et al. Among authors: breukink e. bioRxiv [Preprint]. 2023 May 15:2023.05.15.540765. doi: 10.1101/2023.05.15.540765. bioRxiv. 2023. PMID: 37292624 Free PMC article. Updated. Preprint.
Activities and regulation of peptidoglycan synthases.
Egan AJ, Biboy J, van't Veer I, Breukink E, Vollmer W. Egan AJ, et al. Among authors: breukink e. Philos Trans R Soc Lond B Biol Sci. 2015 Oct 5;370(1679):20150031. doi: 10.1098/rstb.2015.0031. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 26370943 Free PMC article. Review.
Towards the Native Binding Modes of Antibiotics that Target Lipid II.
Medeiros-Silva J, Jekhmane S, Breukink E, Weingarth M. Medeiros-Silva J, et al. Among authors: breukink e. Chembiochem. 2019 Jul 15;20(14):1731-1738. doi: 10.1002/cbic.201800796. Epub 2019 May 22. Chembiochem. 2019. PMID: 30725496 Free PMC article. Review.
Lipid II as a target for antibiotics.
Breukink E, de Kruijff B. Breukink E, et al. Nat Rev Drug Discov. 2006 Apr;5(4):321-32. doi: 10.1038/nrd2004. Nat Rev Drug Discov. 2006. PMID: 16531990 Review.
The enigmatic mode of action of the lantibiotic epilancin 15X.
Wang X, Xu Y, Martin NI, Breukink E. Wang X, et al. Among authors: breukink e. Biochim Biophys Acta Biomembr. 2024 Mar;1866(3):184282. doi: 10.1016/j.bbamem.2024.184282. Epub 2024 Jan 12. Biochim Biophys Acta Biomembr. 2024. PMID: 38218577 Free article. Review.
129 results