Mechanisms of weight loss-induced remission in people with prediabetes: a post-hoc analysis of the randomised, controlled, multicentre Prediabetes Lifestyle Intervention Study (PLIS).
Sandforth A, von Schwartzenberg RJ, Arreola EV, Hanson RL, Sancar G, Katzenstein S, Lange K, Preißl H, Dreher SI, Weigert C, Wagner R, Kantartzis K, Machann J, Schick F, Lehmann R, Peter A, Katsouli N, Ntziachristos V, Dannecker C, Fritsche L, Perakakis N, Heni M, Nawroth PP, Kopf S, Pfeiffer AFH, Kabisch S, Stumvoll M, Schwarz PEH, Hauner H, Lechner A, Seissler J, Yurchenko I, Icks A, Solimena M, Häring HU, Szendroedi J, Schürmann A, de Angelis MH, Blüher M, Roden M, Bornstein SR, Stefan N, Fritsche A, Birkenfeld AL.
Sandforth A, et al.
Lancet Diabetes Endocrinol. 2023 Nov;11(11):798-810. doi: 10.1016/S2213-8587(23)00235-8. Epub 2023 Sep 25.
Lancet Diabetes Endocrinol. 2023.
PMID: 37769677
Clinical Trial.
Responders were defined as people who returned to normal fasting plasma glucose (FPG; <5.6 mmol/L), normal glucose tolerance (<7.8 mmol/L), and HbA(1c) less than 39 mmol/mol after 12 months of lifestyle intervention or placebo or control intervention. Non-responders were de …
Responders were defined as people who returned to normal fasting plasma glucose (FPG; <5.6 mmol/L), normal glucose tolerance (<7.8 mmo …