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Page 1
Showing results for early swath
Search for Earla Swathi instead (1 results)
Ultra-High-Throughput Clinical Proteomics Reveals Classifiers of COVID-19 Infection.
Messner CB, Demichev V, Wendisch D, Michalick L, White M, Freiwald A, Textoris-Taube K, Vernardis SI, Egger AS, Kreidl M, Ludwig D, Kilian C, Agostini F, Zelezniak A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, von Kalle C, Campbell A, Hayward C, Porteous DJ, Marioni RE, Langenberg C, Lilley KS, Kuebler WM, Mülleder M, Drosten C, Suttorp N, Witzenrath M, Kurth F, Sander LE, Ralser M. Messner CB, et al. Cell Syst. 2020 Jul 22;11(1):11-24.e4. doi: 10.1016/j.cels.2020.05.012. Epub 2020 Jun 2. Cell Syst. 2020. PMID: 32619549 Free PMC article.
Our low-cost workflow handles up to 180 samples per day, enables high precision quantification, and reduces batch effects for large-scale and longitudinal studies. We use our platform on samples collected from a cohort of early hospitalized cases of the SARS-CoV-2 pandemic …
Our low-cost workflow handles up to 180 samples per day, enables high precision quantification, and reduces batch effects for large-scale an …
Nitrogen Fixation at Early Mars.
Adams D, Luo Y, Wong ML, Dunn P, Christensen M, Dong C, Hu R, Yung Y. Adams D, et al. Astrobiology. 2021 Aug;21(8):968-980. doi: 10.1089/ast.2020.2273. Epub 2021 Jul 30. Astrobiology. 2021. PMID: 34339294
One possible mechanism for ancient nitrate deposition on Mars is through HNOx formation and rain out in the atmosphere, for which lightning-induced NO is likely the fundamental source. This study investigates nitrogen (N(2)) fixation in early Mars' atmosphere, with implica …
One possible mechanism for ancient nitrate deposition on Mars is through HNOx formation and rain out in the atmosphere, for which lightning- …
SWATH-MS Protocols in Human Diseases.
Chantada-Vázquez MDP, García Vence M, Serna A, Núñez C, Bravo SB. Chantada-Vázquez MDP, et al. Methods Mol Biol. 2021;2259:105-141. doi: 10.1007/978-1-0716-1178-4_7. Methods Mol Biol. 2021. PMID: 33687711
Identification of molecular biomarkers for human diseases is one of the most important disciplines in translational science as it helps to elucidate their origin and early progression. Thus, it is a key factor in better diagnosis, prognosis, and treatment. ...In this chapt …
Identification of molecular biomarkers for human diseases is one of the most important disciplines in translational science as it helps to e …
SWATH Based Quantitative Proteomics Reveals Significant Lipid Metabolism in Early Myopic Guinea Pig Retina.
Bian J, Sze YH, Tse DY, To CH, McFadden SA, Lam CS, Li KK, Lam TC. Bian J, et al. Int J Mol Sci. 2021 Apr 29;22(9):4721. doi: 10.3390/ijms22094721. Int J Mol Sci. 2021. PMID: 33946922 Free PMC article.
Here, to investigate comprehensive retinal protein alternations and underlying molecular events in the early myopic stage, we performed a data-independent Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH) based proteomic analysis coupled with dif …
Here, to investigate comprehensive retinal protein alternations and underlying molecular events in the early myopic stage, we perform …
Tagmentation-based single-cell genomics.
Adey AC. Adey AC. Genome Res. 2021 Oct;31(10):1693-1705. doi: 10.1101/gr.275223.121. Genome Res. 2021. PMID: 34599003 Free PMC article. Review.
In recent years, this has been centered in the single-cell space with a catalog of tagmentation-based assays that have been developed, covering a substantial swath of the regulatory landscape. To date, there have been a number of excellent reviews on single-cell technologi …
In recent years, this has been centered in the single-cell space with a catalog of tagmentation-based assays that have been developed, cover …
Selfish genetic elements.
Ågren JA, Clark AG. Ågren JA, et al. PLoS Genet. 2018 Nov 15;14(11):e1007700. doi: 10.1371/journal.pgen.1007700. eCollection 2018 Nov. PLoS Genet. 2018. PMID: 30439939 Free PMC article. Review.
However, when genes have some control over their own transmission, the rules can change, and so just like all social groups, genomes are vulnerable to selfish behaviour by their parts. Early observations of selfish genetic elements were made almost a century ago, but the t …
However, when genes have some control over their own transmission, the rules can change, and so just like all social groups, genomes are vul …
What Is Antagonistic Pleiotropy?
Mitteldorf J. Mitteldorf J. Biochemistry (Mosc). 2019 Dec;84(12):1458-1468. doi: 10.1134/S0006297919120058. Biochemistry (Mosc). 2019. PMID: 31870250 Review.
In this standard view, aging exists because the benefits of enhanced fertility early in life are linked logically or physically to the long-term deterioration of the body, and evolution has been compelled to accept the latter as a cost of the former. ...Indeed, biological …
In this standard view, aging exists because the benefits of enhanced fertility early in life are linked logically or physically to th …
Early lipid changes in acute kidney injury using SWATH lipidomics coupled with MALDI tissue imaging.
Rao S, Walters KB, Wilson L, Chen B, Bolisetty S, Graves D, Barnes S, Agarwal A, Kabarowski JH. Rao S, et al. Am J Physiol Renal Physiol. 2016 May 15;310(10):F1136-47. doi: 10.1152/ajprenal.00100.2016. Epub 2016 Feb 24. Am J Physiol Renal Physiol. 2016. PMID: 26911846 Free PMC article.
Although our understanding of AKI at the molecular level remains limited due to its complex pathophysiology, recent advances in both quantitative and spatial mass spectrometric approaches offer new opportunities to assess the significance of renal metabolomic changes in AKI model …
Although our understanding of AKI at the molecular level remains limited due to its complex pathophysiology, recent advances in both quantit …
Proteomics in Inherited Metabolic Disorders.
Chantada-Vázquez MDP, Bravo SB, Barbosa-Gouveia S, Alvarez JV, Couce ML. Chantada-Vázquez MDP, et al. Int J Mol Sci. 2022 Nov 25;23(23):14744. doi: 10.3390/ijms232314744. Int J Mol Sci. 2022. PMID: 36499071 Free PMC article. Review.
The number of treatable IMDs has increased in recent years, making early diagnosis and a better understanding of the natural history of the disease more important than ever. ...Proteomics is a particularly promising approach to help obtain more information on rare genetic …
The number of treatable IMDs has increased in recent years, making early diagnosis and a better understanding of the natural history …
Polarization in America: two possible futures.
Heltzel G, Laurin K. Heltzel G, et al. Curr Opin Behav Sci. 2020 Aug;34:179-184. doi: 10.1016/j.cobeha.2020.03.008. Epub 2020 May 6. Curr Opin Behav Sci. 2020. PMID: 32391408 Free PMC article. Review.
This worry is understandable: up to a point, polarization can help democracies, but when it becomes too vast, such that entire swaths of the population refuse to consider each other's views, this thwarts democratic methods for solving societal problems. ...On one hand, pol …
This worry is understandable: up to a point, polarization can help democracies, but when it becomes too vast, such that entire swaths
136 results