Alzheimer's disease as an autoimmune disorder of innate immunity endogenously modulated by tryptophan metabolites.
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Alzheimers Dement (N Y). 2022 Apr 6;8(1):e12283. doi: 10.1002/trc2.12283. eCollection 2022.
Alzheimers Dement (N Y). 2022.
PMID: 35415204
Free PMC article.
Next, 471 new chemical entities were designed and synthesized to probe the pathways identified by these molecular mechanism studies and to provide prototypic starting points in the development of small-molecule therapeutics for AD. RESULTS: In response to various stimuli (e …
Next, 471 new chemical entities were designed and synthesized to probe the pathways identified by these molecular mechanism studies and to p …