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Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma.
Mellinghoff IK, van den Bent MJ, Blumenthal DT, Touat M, Peters KB, Clarke J, Mendez J, Yust-Katz S, Welsh L, Mason WP, Ducray F, Umemura Y, Nabors B, Holdhoff M, Hottinger AF, Arakawa Y, Sepulveda JM, Wick W, Soffietti R, Perry JR, Giglio P, de la Fuente M, Maher EA, Schoenfeld S, Zhao D, Pandya SS, Steelman L, Hassan I, Wen PY, Cloughesy TF; INDIGO Trial Investigators. Mellinghoff IK, et al. N Engl J Med. 2023 Aug 17;389(7):589-601. doi: 10.1056/NEJMoa2304194. Epub 2023 Jun 4. N Engl J Med. 2023. PMID: 37272516 Clinical Trial.
Responsive deep brain stimulation guided by ventral striatal electrophysiology of obsession durably ameliorates compulsion.
Nho YH, Rolle CE, Topalovic U, Shivacharan RS, Cunningham TN, Hiller S, Batista D, Feng A, Espil FM, Kratter IH, Bhati MT, Kellogg M, Raslan AM, Williams NR, Garnett J, Pesaran B, Oathes DJ, Suthana N, Barbosa DAN, Halpern CH. Nho YH, et al. Neuron. 2024 Jan 3;112(1):73-83.e4. doi: 10.1016/j.neuron.2023.09.034. Epub 2023 Oct 20. Neuron. 2024. PMID: 37865084 Free article.
New quinoline-2-one/pyrazole derivatives; design, synthesis, molecular docking, anti-apoptotic evaluation, and caspase-3 inhibition assay.
Aly AA, Sayed SM, Abdelhafez EMN, Abdelhafez SMN, Abdelzaher WY, Raslan MA, Ahmed AE, Thabet K, El-Reedy AAM, Brown AB, Bräse S. Aly AA, et al. Bioorg Chem. 2020 Jan;94:103348. doi: 10.1016/j.bioorg.2019.103348. Epub 2019 Oct 9. Bioorg Chem. 2020. PMID: 31699387
Additionally, colonic histopathological investigation was performed to all targeted compounds that indicates H&E sections of compounds 6a and 6f revealed apparent normal colonic cells while compound 6e showed dilated blood vessels with more apoptotic cells if co …
Additionally, colonic histopathological investigation was performed to all targeted compounds that indicates H&E sections …
Flexible, scalable, high channel count stereo-electrode for recording in the human brain.
Lee K, Paulk AC, Ro YG, Cleary DR, Tonsfeldt KJ, Kfir Y, Pezaris JS, Tchoe Y, Lee J, Bourhis AM, Vatsyayan R, Martin JR, Russman SM, Yang JC, Baohan A, Richardson RM, Williams ZM, Fried SI, Hoi Sang U, Raslan AM, Ben-Haim S, Halgren E, Cash SS, Dayeh SA. Lee K, et al. Nat Commun. 2024 Jan 17;15(1):218. doi: 10.1038/s41467-023-43727-9. Nat Commun. 2024. PMID: 38233418 Free PMC article.
Safety and diagnostic efficacy of gadoteridol for magnetic resonance imaging of the brain and spine in children 2 years of age and younger.
Shah CC, Spampinato MV, Parmar HA, Raslan OA, Tomà P, Lin DDM, Vymazal J, Colosimo C, Enterline DS. Shah CC, et al. Pediatr Radiol. 2021 Sep;51(10):1895-1906. doi: 10.1007/s00247-021-05069-w. Epub 2021 May 5. Pediatr Radiol. 2021. PMID: 33950270 Free PMC article.
Safety data were assessed for acute/subacute adverse events in the 48 h following gadoteridol administration and, when available, vital signs, electrocardiogram (ECG) and clinical laboratory values obtained from blood samples taken from 48 h before until 48 h
Safety data were assessed for acute/subacute adverse events in the 48 h following gadoteridol administration and, when available, vit …
Distinguishing Extravascular from Intravascular Ferumoxytol Pools within the Brain: Proof of Concept in Patients with Treated Glioblastoma.
Barajas RF Jr, Schwartz D, McConnell HL, Kersch CN, Li X, Hamilton BE, Starkey J, Pettersson DR, Nickerson JP, Pollock JM, Fu RF, Horvath A, Szidonya L, Varallyay CG, Jaboin JJ, Raslan AM, Dogan A, Cetas JS, Ciporen J, Han SJ, Ambady P, Muldoon LL, Woltjer R, Rooney WD, Neuwelt EA. Barajas RF Jr, et al. AJNR Am J Neuroradiol. 2020 Jul;41(7):1193-1200. doi: 10.3174/ajnr.A6600. Epub 2020 Jun 11. AJNR Am J Neuroradiol. 2020. PMID: 32527840 Free PMC article.