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Process development exploiting competitive adsorption-based displacement effects in monoclonal antibody aggregate removal-A new high-throughput screening procedure for membrane chromatography.
Biotechnol Appl Biochem. 2022 Aug;69(4):1663-1678. doi: 10.1002/bab.2236. Epub 2021 Aug 22.
Biotechnol Appl Biochem. 2022.
PMID: 34365669
Streamlined process development procedure incorporating the selection of various stationary phase types established in a mAb aggregate reduction study with different mixed mode ligands.
Stein D, Thom V, Hubbuch J.
Stein D, et al.
Biotechnol Prog. 2022 Mar;38(2):e3230. doi: 10.1002/btpr.3230. Epub 2022 Jan 6.
Biotechnol Prog. 2022.
PMID: 34967498
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High throughput screening setup of a scale-down device for membrane chromatography-aggregate removal of monoclonal antibodies.
Stein D, Thom V, Hubbuch J.
Stein D, et al.
Biotechnol Prog. 2020 Nov;36(6):e3055. doi: 10.1002/btpr.3055. Epub 2020 Aug 29.
Biotechnol Prog. 2020.
PMID: 32710474
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Evaluation of Continuous Membrane Chromatography Concepts with an Enhanced Process Simulation Approach.
Zobel-Roos S, Stein D, Strube J.
Zobel-Roos S, et al. Among authors: stein d.
Antibodies (Basel). 2018 Mar 2;7(1):13. doi: 10.3390/antib7010013.
Antibodies (Basel). 2018.
PMID: 31544865
Free PMC article.
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