Transfusional chagas disease: parasitological and serological monitoring of an infected recipient and blood donor

Clin Infect Dis. 2008 Mar 1;46(5):e44-7. doi: 10.1086/527448.

Abstract

Chagas disease is endemic to Latin America, but human migration is extending its distribution. This report describes the parasitological and serological course of disease in a Spanish patient fatally infected via a blood product transfusion, as well as the monitoring of the donor. Before undergoing immunosuppression, multitransfused patients should be screened for anti-Trypanosoma cruzi antibodies.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Antibodies, Protozoan / blood
  • Blood Donors
  • Chagas Disease / immunology
  • Chagas Disease / parasitology
  • Chagas Disease / transmission*
  • DNA, Protozoan / blood
  • Enzyme-Linked Immunosorbent Assay
  • Fatal Outcome
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polymerase Chain Reaction
  • Spain
  • Transfusion Reaction*
  • Trypanosoma cruzi / immunology

Substances

  • Antibodies, Protozoan
  • DNA, Protozoan