Selenium, a ubiquitous non-metal in nature, is potentially toxic to natural ecosystems due to its bioaccumulation potential. Due to increased monitoring and enforcement of selenium regulations, the need to be able to measure and treat selenium efficiently has taken on an increased importance. The principal aqueous forms of inorganic selenium are selenite (Se(IV)) and selenate (Se(VI)). Selenate, due to its high mobility and lack of affinity to conventional adsorbents, is typically much more difficult to treat and remove. To address both measurement and removal, an analytical method is reported for quantification of selenium in wastewater (WW) using UV-Vis spectrophotometer followed by removal studies using advanced oxidation processes (AOPs). Malachite green and azure blue were selected for colorimetric analysis using UV-Vis. Malachite green indicator showed the best results for analysis. The reported UV-Vis method was applied to establish the effect of AOPs on selenium removal. It was noted that all of the AOP treated samples showed removal of selenium and it was established that the UV-Vis method has a lower limit of detection at 2 mg/L. Further, through this study, it was found that the chemical cavitation yield and selenium removal efficiency peaked at low frequency ultrasound of 40 kHz.