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Page 1
Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.
Kolijn D, Pabel S, Tian Y, Lódi M, Herwig M, Carrizzo A, Zhazykbayeva S, Kovács Á, Fülöp GÁ, Falcão-Pires I, Reusch PH, Linthout SV, Papp Z, van Heerebeek L, Vecchione C, Maier LS, Ciccarelli M, Tschöpe C, Mügge A, Bagi Z, Sossalla S, Hamdani N. Kolijn D, et al. Cardiovasc Res. 2021 Jan 21;117(2):495-507. doi: 10.1093/cvr/cvaa123. Cardiovasc Res. 2021. PMID: 32396609
Methylation of the Hippo effector YAP by the methyltransferase SETD7 drives myocardial ischaemic injury: a translational study.
Ambrosini S, Montecucco F, Kolijn D, Pedicino D, Akhmedov A, Mohammed SA, Herwig M, Gorica E, Szabó PL, Weber L, Russo G, Vinci R, Matter CM, Liuzzo G, Brown PJ, Rossi FMV, Camici GG, Sciarretta S, Beltrami AP, Crea F, Podesser B, Lüscher TF, Kiss A, Ruschitzka F, Hamdani N, Costantino S, Paneni F. Ambrosini S, et al. Among authors: kolijn d. Cardiovasc Res. 2023 Jan 18;118(17):3374-3385. doi: 10.1093/cvr/cvac102. Cardiovasc Res. 2023. PMID: 35709329
SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress.
Tangos M, Budde H, Kolijn D, Sieme M, Zhazykbayeva S, Lódi M, Herwig M, Gömöri K, Hassoun R, Robinson EL, Meister TL, Jaquet K, Kovács Á, Mustroph J, Evert K, Babel N, Fagyas M, Lindner D, Püschel K, Westermann D, Mannherz HG, Paneni F, Pfaender S, Tóth A, Mügge A, Sossalla S, Hamdani N. Tangos M, et al. Among authors: kolijn d. Int J Cardiol. 2022 Sep 1;362:196-205. doi: 10.1016/j.ijcard.2022.05.055. Epub 2022 May 26. Int J Cardiol. 2022. PMID: 35643215 Free PMC article.
Myotube growth is associated with cancer-like metabolic reprogramming and is limited by phosphoglycerate dehydrogenase.
Stadhouders LEM, Smith JAB, Gabriel BM, Verbrugge SAJ, Hammersen TD, Kolijn D, Vogel ISP, Mohamed AD, de Wit GMJ, Offringa C, Hoogaars WMH, Gehlert S, Wackerhage H, Jaspers RT. Stadhouders LEM, et al. Among authors: kolijn d. Exp Cell Res. 2023 Dec 15;433(2):113820. doi: 10.1016/j.yexcr.2023.113820. Epub 2023 Oct 23. Exp Cell Res. 2023. PMID: 37879549 Free article.
Modulation of Titin-Based Stiffness in Hypertrophic Cardiomyopathy via Protein Kinase D.
Herwig M, Kolijn D, Lódi M, Hölper S, Kovács Á, Papp Z, Jaquet K, Haldenwang P, Dos Remedios C, Reusch PH, Mügge A, Krüger M, Fielitz J, Linke WA, Hamdani N. Herwig M, et al. Among authors: kolijn d. Front Physiol. 2020 Apr 15;11:240. doi: 10.3389/fphys.2020.00240. eCollection 2020. Front Physiol. 2020. PMID: 32351396 Free PMC article.
Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model.
Waddingham MT, Sonobe T, Tsuchimochi H, Edgley AJ, Sukumaran V, Chen YC, Hansra SS, Schwenke DO, Umetani K, Aoyama K, Yagi N, Kelly DJ, Gaderi S, Herwig M, Kolijn D, Mügge A, Paulus WJ, Ogo T, Shirai M, Hamdani N, Pearson JT. Waddingham MT, et al. Among authors: kolijn d. J Mol Cell Cardiol. 2019 Dec;137:119-131. doi: 10.1016/j.yjmcc.2019.10.005. Epub 2019 Oct 28. J Mol Cell Cardiol. 2019. PMID: 31669609 Free article.
The Interplay between S-Glutathionylation and Phosphorylation of Cardiac Troponin I and Myosin Binding Protein C in End-Stage Human Failing Hearts.
Budde H, Hassoun R, Tangos M, Zhazykbayeva S, Herwig M, Varatnitskaya M, Sieme M, Delalat S, Sultana I, Kolijn D, Gömöri K, Jarkas M, Lódi M, Jaquet K, Kovács Á, Mannherz HG, Sequeira V, Mügge A, Leichert LI, Sossalla S, Hamdani N. Budde H, et al. Among authors: kolijn d. Antioxidants (Basel). 2021 Jul 16;10(7):1134. doi: 10.3390/antiox10071134. Antioxidants (Basel). 2021. PMID: 34356367 Free PMC article.
Interventricular Differences of Signaling Pathways-Mediated Regulation of Cardiomyocyte Function in Response to High Oxidative Stress in the Post-Ischemic Failing Rat Heart.
Kovács Á, Herwig M, Budde H, Delalat S, Kolijn D, Bódi B, Hassoun R, Tangos M, Zhazykbayeva S, Balogh Á, Czuriga D, Van Linthout S, Tschöpe C, Dhalla NS, Mügge A, Tóth A, Papp Z, Barta J, Hamdani N. Kovács Á, et al. Among authors: kolijn d. Antioxidants (Basel). 2021 Jun 16;10(6):964. doi: 10.3390/antiox10060964. Antioxidants (Basel). 2021. PMID: 34208541 Free PMC article.
Enhanced Cardiomyocyte Function in Hypertensive Rats With Diastolic Dysfunction and Human Heart Failure Patients After Acute Treatment With Soluble Guanylyl Cyclase (sGC) Activator.
Kolijn D, Kovács Á, Herwig M, Lódi M, Sieme M, Alhaj A, Sandner P, Papp Z, Reusch PH, Haldenwang P, Falcão-Pires I, Linke WA, Jaquet K, Van Linthout S, Mügge A, Tschöpe C, Hamdani N. Kolijn D, et al. Front Physiol. 2020 May 25;11:345. doi: 10.3389/fphys.2020.00345. eCollection 2020. Front Physiol. 2020. PMID: 32523538 Free PMC article.