Chronic cadmium exposure triggered ferroptosis by perturbing the STEAP3-mediated glutathione redox balance linked to altered metabolomic signatures in humans.
Deng P, Li J, Lu Y, Hao R, He M, Li M, Tan M, Gao P, Wang L, Hong H, Tao J, Lu M, Chen C, Ma Q, Yue Y, Wang H, Tian L, Xie J, Chen M, Luo Y, Yu Z, Zhou Z, Pi H.
Deng P, et al.
Sci Total Environ. 2023 Dec 20;905:167039. doi: 10.1016/j.scitotenv.2023.167039. Epub 2023 Sep 14.
Sci Total Environ. 2023.
PMID: 37716689
In conclusion, this study provides the first evidence indicating that chronic Cd exposure triggers ferroptosis and renal dysfunction that depend on STEAP3-mediated glutathione redox imbalance, greatly increasing our understanding of the metabolic reprogramming induced by C …
In conclusion, this study provides the first evidence indicating that chronic Cd exposure triggers ferroptosis and renal dysfunction that …