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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 4
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2005 5
2006 5
2007 6
2008 4
2009 7
2010 6
2011 7
2012 4
2013 3
2015 2
2016 1
2017 2
2018 8
2019 4
2020 3
2021 1
2023 2
2024 0

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Page 1
Relevance of Half-Life in Drug Design.
Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. J Med Chem. 2018 May 24;61(10):4273-4282. doi: 10.1021/acs.jmedchem.7b00969. Epub 2017 Nov 17. J Med Chem. 2018. PMID: 29112446
Clearance in Drug Design.
Smith DA, Beaumont K, Maurer TS, Di L. Smith DA, et al. J Med Chem. 2019 Mar 14;62(5):2245-2255. doi: 10.1021/acs.jmedchem.8b01263. Epub 2018 Oct 17. J Med Chem. 2019. PMID: 30281973 Review.
Why do metabolites circulate?
Smith DA, Dalvie D. Smith DA, et al. Xenobiotica. 2012 Jan;42(1):107-26. doi: 10.3109/00498254.2011.630110. Epub 2011 Nov 24. Xenobiotica. 2012. PMID: 22115420 Review.
Which metabolites circulate?
Loi CM, Smith DA, Dalvie D. Loi CM, et al. Among authors: smith da. Drug Metab Dispos. 2013 May;41(5):933-51. doi: 10.1124/dmd.112.050278. Epub 2013 Mar 1. Drug Metab Dispos. 2013. PMID: 23454828
Discovery and ADMET: Where are we now.
Smith DA. Smith DA. Curr Top Med Chem. 2011;11(4):467-81. doi: 10.2174/156802611794480909. Curr Top Med Chem. 2011. PMID: 21320070 Review.
Importance of target-mediated drug disposition for small molecules.
Smith DA, van Waterschoot RAB, Parrott NJ, Olivares-Morales A, Lavé T, Rowland M. Smith DA, et al. Drug Discov Today. 2018 Dec;23(12):2023-2030. doi: 10.1016/j.drudis.2018.06.010. Epub 2018 Jun 19. Drug Discov Today. 2018. PMID: 29928850 Review.
The Critical Role of Passive Permeability in Designing Successful Drugs.
Di L, Artursson P, Avdeef A, Benet LZ, Houston JB, Kansy M, Kerns EH, Lennernäs H, Smith DA, Sugano K. Di L, et al. Among authors: smith da. ChemMedChem. 2020 Oct 19;15(20):1862-1874. doi: 10.1002/cmdc.202000419. Epub 2020 Sep 10. ChemMedChem. 2020. PMID: 32743945 Review.
70 results