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Human milk nutrient fortifiers alter the developing gastrointestinal microbiota of very-low-birth-weight infants.
Asbury MR, Shama S, Sa JY, Bando N, Butcher J, Comelli EM, Copeland JK, Forte V, Kiss A, Sherman PM, Stintzi A, Taibi A, Tomlinson C, Unger S, Wang PW, O'Connor DL; OptiMoM Feeding Group. Asbury MR, et al. Cell Host Microbe. 2022 Sep 14;30(9):1328-1339.e5. doi: 10.1016/j.chom.2022.07.011. Epub 2022 Aug 19. Cell Host Microbe. 2022. PMID: 35987195 Free article. Clinical Trial.
Low Serum Vitamin B-12 Concentrations Are Prevalent in a Cohort of Pregnant Canadian Women.
Visentin CE, Masih SP, Plumptre L, Schroder TH, Sohn KJ, Ly A, Lausman AY, Berger H, Croxford R, Lamers Y, Kim YI, O'Connor DL. Visentin CE, et al. J Nutr. 2016 May;146(5):1035-42. doi: 10.3945/jn.115.226845. Epub 2016 Apr 13. J Nutr. 2016. PMID: 27075906 Free article.
BACKGROUND: Among Canadian women of reproductive age, 5% and 20% have serum vitamin B-12 concentrations indicative of deficiency (<148 pmol/L) and marginal status (148-220 pmol/L), respectively. Given the association between suboptimal vitamin B-12 and adverse pr …
BACKGROUND: Among Canadian women of reproductive age, 5% and 20% have serum vitamin B-12 concentrations indicative of deficiency (<148 pm …
Neither folic acid supplementation nor pregnancy affects the distribution of folate forms in the red blood cells of women.
Hartman BA, Fazili Z, Pfeiffer CM, O'Connor DL. Hartman BA, et al. J Nutr. 2014 Sep;144(9):1364-9. doi: 10.3945/jn.113.189233. Epub 2014 Jul 2. J Nutr. 2014. PMID: 24991041 Free PMC article. Clinical Trial.

The mean SD RBC folate concentration of the NPW-0 group (890 530 nmol/L) was lower than the NPW-1 (1660 350 nmol/L) and NPW-5 (1980 570 nmol/L) groups as assessed by microbiologic assay (n = 26, P < 0.0022). ...We detected 5-methyl-THF [limit of detection

…
The mean SD RBC folate concentration of the NPW-0 group (890 530 nmol/L) was lower than the NPW-1 (1660 350 nmol/L) and NPW-5 …
Low-dose daily folic acid (400 μg) supplementation does not affect regulation of folate transporters found present throughout the terminal ileum and colon of humans: a randomized clinical trial.
Farrell CC, Khanna S, Hoque MT, Plaga A, Basset N, Syed I, Biouss G, Aufreiter S, Marcon N, Bendayan R, Kim YI, O'Connor DL. Farrell CC, et al. Am J Clin Nutr. 2024 Mar;119(3):809-820. doi: 10.1016/j.ajcnut.2023.12.018. Epub 2023 Dec 28. Am J Clin Nutr. 2024. PMID: 38157986 Clinical Trial.
Mean SD red blood cell folate at 16 wk was 1765 426 and 911 242 nmol/L in the 400 and 0 mug folic acid group, respectively (P < 0.0001). ...

Mean SD red blood cell folate at 16 wk was 1765 426 and 911 242 nmol/L in the 400 and 0 mug folic acid group, respectively (P < 0.

…
Growth and development in preterm infants fed long-chain polyunsaturated fatty acids: a prospective, randomized controlled trial.
O'Connor DL, Hall R, Adamkin D, Auestad N, Castillo M, Connor WE, Connor SL, Fitzgerald K, Groh-Wargo S, Hartmann EE, Jacobs J, Janowsky J, Lucas A, Margeson D, Mena P, Neuringer M, Nesin M, Singer L, Stephenson T, Szabo J, Zemon V; Ross Preterm Lipid Study. O'Connor DL, et al. Pediatrics. 2001 Aug;108(2):359-71. doi: 10.1542/peds.108.2.359. Pediatrics. 2001. PMID: 11483801 Clinical Trial.
Growth and development of premature infants fed predominantly human milk, predominantly premature infant formula, or a combination of human milk and premature formula.
O'Connor DL, Jacobs J, Hall R, Adamkin D, Auestad N, Castillo M, Connor WE, Connor SL, Fitzgerald K, Groh-Wargo S, Hartmann EE, Janowsky J, Lucas A, Margeson D, Mena P, Neuringer M, Ross G, Singer L, Stephenson T, Szabo J, Zemon V. O'Connor DL, et al. J Pediatr Gastroenterol Nutr. 2003 Oct;37(4):437-46. doi: 10.1097/00005176-200310000-00008. J Pediatr Gastroenterol Nutr. 2003. PMID: 14508214 Clinical Trial.
If human milk was fed before hospital discharge, it was fortified (3,050-3,300 kJ/L, 22-24 kcal/oz). As infants were weaned from human milk, they were fed nutrient-enriched formula with or without arachidonic and docosahexaenoic acids (3,300 kJ/L before term, 3,050 …
If human milk was fed before hospital discharge, it was fortified (3,050-3,300 kJ/L, 22-24 kcal/oz). As infants were weaned from huma …
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