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Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.
Foliaki ST, Lewis V, Islam AMT, Ellett LJ, Senesi M, Finkelstein DI, Roberts B, Lawson VA, Adlard PA, Collins SJ. Foliaki ST, et al. Among authors: finkelstein di. PLoS Pathog. 2019 Apr 10;15(4):e1007712. doi: 10.1371/journal.ppat.1007712. eCollection 2019 Apr. PLoS Pathog. 2019. PMID: 30970042 Free PMC article.
Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.
Foliaki ST, Lewis V, Finkelstein DI, Lawson V, Coleman HA, Senesi M, Islam AMT, Chen F, Sarros S, Roberts B, Adlard PA, Collins SJ. Foliaki ST, et al. Among authors: finkelstein di. PLoS Pathog. 2018 Aug 8;14(8):e1007214. doi: 10.1371/journal.ppat.1007214. eCollection 2018 Aug. PLoS Pathog. 2018. PMID: 30089152 Free PMC article.