The pan-inhibitor of Aurora kinases danusertib induces apoptosis and autophagy and suppresses epithelial-to-mesenchymal transition in human breast cancer cells.
Li JP, Yang YX, Liu QL, Zhou ZW, Pan ST, He ZX, Zhang X, Yang T, Pan SY, Duan W, He SM, Chen XW, Qiu JX, Zhou SF.
Li JP, et al.
Drug Des Devel Ther. 2015 Feb 17;9:1027-62. doi: 10.2147/DDDT.S74412. eCollection 2015.
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PMID: 25733818
Free PMC article.
Notably, Danu showed lower cytotoxicity toward normal breast epithelial MCF10A cells. ...Danu may represent a promising anticancer agent for breast cancer treatment. ...
Notably, Danu showed lower cytotoxicity toward normal breast epithelial MCF10A cells. ...Danu may represent a promising antica …