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Year Number of Results
2014 2
2015 2
2016 1
2017 1
2019 1
2020 12
2021 6
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2023 5
2024 1

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Mutations in the SARS-CoV-2 RNA-dependent RNA polymerase confer resistance to remdesivir by distinct mechanisms.
Stevens LJ, Pruijssers AJ, Lee HW, Gordon CJ, Tchesnokov EP, Gribble J, George AS, Hughes TM, Lu X, Li J, Perry JK, Porter DP, Cihlar T, Sheahan TP, Baric RS, Götte M, Denison MR. Stevens LJ, et al. Among authors: porter dp. Sci Transl Med. 2022 Aug 3;14(656):eabo0718. doi: 10.1126/scitranslmed.abo0718. Epub 2022 Aug 3. Sci Transl Med. 2022. PMID: 35482820 Free PMC article.
Oral administration of obeldesivir protects nonhuman primates against Sudan ebolavirus.
Cross RW, Woolsey C, Chu VC, Babusis D, Bannister R, Vermillion MS, Geleziunas R, Barrett KT, Bunyan E, Nguyen AQ, Cihlar T, Porter DP, Prasad AN, Deer DJ, Borisevich V, Agans KN, Martinez J, Harrison MB, Dobias NS, Fenton KA, Bilello JP, Geisbert TW. Cross RW, et al. Among authors: porter dp. Science. 2024 Mar 15;383(6688):eadk6176. doi: 10.1126/science.adk6176. Epub 2024 Mar 15. Science. 2024. PMID: 38484056
Expanded profiling of Remdesivir as a broad-spectrum antiviral and low potential for interaction with other medications in vitro.
Radoshitzky SR, Iversen P, Lu X, Zou J, Kaptein SJF, Stuthman KS, Van Tongeren SA, Steffens J, Gong R, Truong H, Sapre AA, Yang H, Xie X, Chia JJ, Song ZJ, Leventhal SM, Chan J, Shornikov A, Zhang X, Cowfer D, Yu H, Warren T, Cihlar T, Porter DP, Neyts J, Shi PY, Wells J, Bilello JP, Feng JY. Radoshitzky SR, et al. Among authors: porter dp. Sci Rep. 2023 Feb 23;13(1):3131. doi: 10.1038/s41598-023-29517-9. Sci Rep. 2023. PMID: 36823196 Free PMC article.
Remdesivir efficacy against yellow fever in a hamster model.
Julander JG, Bunyan E, Jordan R, Porter DP. Julander JG, et al. Among authors: porter dp. Antiviral Res. 2022 Jul;203:105331. doi: 10.1016/j.antiviral.2022.105331. Epub 2022 May 6. Antiviral Res. 2022. PMID: 35533777
A Phase 2b, Randomized, Double-blind, Placebo-Controlled Multicenter Study Evaluating Antiviral Effects, Pharmacokinetics, Safety, and Tolerability of Presatovir in Hematopoietic Cell Transplant Recipients with Respiratory Syncytial Virus Infection of the Lower Respiratory Tract.
Marty FM, Chemaly RF, Mullane KM, Lee DG, Hirsch HH, Small CB, Bergeron A, Shoham S, Ljungman P, Waghmare A, Blanchard E, Kim YJ, McKevitt M, Porter DP, Jordan R, Guo Y, German P, Boeckh M, Watkins TR, Chien JW, Dadwal SS. Marty FM, et al. Among authors: porter dp. Clin Infect Dis. 2020 Dec 31;71(11):2787-2795. doi: 10.1093/cid/ciz1167. Clin Infect Dis. 2020. PMID: 31915807 Free PMC article. Clinical Trial.
Combination therapy protects macaques against advanced Marburg virus disease.
Cross RW, Bornholdt ZA, Prasad AN, Borisevich V, Agans KN, Deer DJ, Abelson DM, Kim DH, Shestowsky WS, Campbell LA, Bunyan E, Geisbert JB, Fenton KA, Zeitlin L, Porter DP, Geisbert TW. Cross RW, et al. Among authors: porter dp. Nat Commun. 2021 Mar 25;12(1):1891. doi: 10.1038/s41467-021-22132-0. Nat Commun. 2021. PMID: 33767178 Free PMC article.
40 results