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Page 1
Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer's Disease.
Molecules. 2018 Dec 7;23(12):3230. doi: 10.3390/molecules23123230.
Molecules. 2018.
PMID: 30544533
Free PMC article.
Review.
Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation.
Matera C, Kauk M, Cirillo D, Maspero M, Papotto C, Volpato D, Holzgrabe U, De Amici M, Hoffmann C, Dallanoce C.
Matera C, et al. Among authors: volpato d.
Molecules. 2023 Mar 6;28(5):2407. doi: 10.3390/molecules28052407.
Molecules. 2023.
PMID: 36903650
Free PMC article.
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The Role of Orthosteric Building Blocks of Bitopic Ligands for Muscarinic M1 Receptors.
Volpato D, Kauk M, Messerer R, Bermudez M, Wolber G, Bock A, Hoffmann C, Holzgrabe U.
Volpato D, et al.
ACS Omega. 2020 Dec 1;5(49):31706-31715. doi: 10.1021/acsomega.0c04220. eCollection 2020 Dec 15.
ACS Omega. 2020.
PMID: 33344823
Free PMC article.
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Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors.
Maspero M, Volpato D, Cirillo D, Yuan Chen N, Messerer R, Sotriffer C, De Amici M, Holzgrabe U, Dallanoce C.
Maspero M, et al. Among authors: volpato d.
Bioorg Chem. 2020 Mar;96:103633. doi: 10.1016/j.bioorg.2020.103633. Epub 2020 Jan 30.
Bioorg Chem. 2020.
PMID: 32032848
Free article.
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FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor.
Messerer R, Kauk M, Volpato D, Alonso Canizal MC, Klöckner J, Zabel U, Nuber S, Hoffmann C, Holzgrabe U.
Messerer R, et al. Among authors: volpato d.
ACS Chem Biol. 2017 Mar 17;12(3):833-843. doi: 10.1021/acschembio.6b00828. Epub 2017 Feb 6.
ACS Chem Biol. 2017.
PMID: 28117571
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