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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma.
Sonntag R, Giebeler N, Nevzorova YA, Bangen JM, Fahrenkamp D, Lambertz D, Haas U, Hu W, Gassler N, Cubero FJ, Müller-Newen G, Abdallah AT, Weiskirchen R, Ticconi F, Costa IG, Barbacid M, Trautwein C, Liedtke C. Sonntag R, et al. Among authors: lambertz d. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9282-9287. doi: 10.1073/pnas.1807155115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150405 Free PMC article.
Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury.
Liedtke C, Bangen JM, Freimuth J, Beraza N, Lambertz D, Cubero FJ, Hatting M, Karlmark KR, Streetz KL, Krombach GA, Tacke F, Gassler N, Riethmacher D, Trautwein C. Liedtke C, et al. Among authors: lambertz d. Gastroenterology. 2011 Dec;141(6):2176-87. doi: 10.1053/j.gastro.2011.08.037. Epub 2011 Aug 28. Gastroenterology. 2011. PMID: 21878202
Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice.
Hao F, Cubero FJ, Ramadori P, Liao L, Haas U, Lambertz D, Sonntag R, Bangen JM, Gassler N, Hoss M, Streetz KL, Reissing J, Zimmermann HW, Trautwein C, Liedtke C, Nevzorova YA. Hao F, et al. Among authors: lambertz d. Cell Death Dis. 2017 Oct 26;8(10):e3152. doi: 10.1038/cddis.2017.532. Cell Death Dis. 2017. PMID: 29072704 Free PMC article.
11 results