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1979 1
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2003 1
2004 1
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2007 1
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2021 2
2024 0

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Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2021 Feb 13;397(10274):605-612. doi: 10.1016/S0140-6736(21)00149-5. Epub 2021 Feb 2. Lancet. 2021. PMID: 33545096 Free PMC article. Clinical Trial.
Azithromycin use in patients admitted to hospital with COVID-19 should be restricted to patients in whom there is a clear antimicrobial indication. FUNDING: UK Research and Innovation (Medical Research Council) and National Institute of Health Research....
Azithromycin use in patients admitted to hospital with COVID-19 should be restricted to patients in whom there is a clear antimicrobi …
An integrative method to normalize RNA-Seq data.
Filloux C, Cédric M, Romain P, Lionel F, Christophe K, Dominique R, Abderrahman M, Daniel P. Filloux C, et al. Among authors: daniel p. BMC Bioinformatics. 2014 Jun 14;15:188. doi: 10.1186/1471-2105-15-188. BMC Bioinformatics. 2014. PMID: 24929920 Free PMC article.
In order to correct some of them, several normalization approaches have emerged, differing both in the statistical strategy employed and in the type of corrected biases. However, there is no clear standard normalization method. RESULTS: We present a novel methodology to no …
In order to correct some of them, several normalization approaches have emerged, differing both in the statistical strategy employed and in …
Inhibition of Aquaporin 4 Decreases Amyloid Aβ40 Drainage Around Cerebral Vessels.
Rosu GC, Catalin B, Balseanu TA, Laurentiu M, Claudiu M, Kumar-Singh S, Daniel P. Rosu GC, et al. Among authors: daniel p. Mol Neurobiol. 2020 Nov;57(11):4720-4734. doi: 10.1007/s12035-020-02044-8. Epub 2020 Aug 11. Mol Neurobiol. 2020. PMID: 32783141 Free PMC article.
While deletion of AQP4 is shown to reduce amyloid-beta (Abeta) clearance and exacerbate Abeta peptide accumulation in plaques and vessels of Alzheimer's disease mouse models, the mechanism and clearing pathways involved are debated. Here, we investigated how inhibiting the …
While deletion of AQP4 is shown to reduce amyloid-beta (Abeta) clearance and exacerbate Abeta peptide accumulation in plaques and vessels of …
NF-κB p65 regulates hepatic lipogenesis by promoting nuclear entry of ChREBP in response to a high carbohydrate diet.
Daniel PV, Dogra S, Rawat P, Choubey A, Khan AS, Rajak S, Kamthan M, Mondal P. Daniel PV, et al. J Biol Chem. 2021 Jan-Jun;296:100714. doi: 10.1016/j.jbc.2021.100714. Epub 2021 Apr 27. J Biol Chem. 2021. PMID: 33930463 Free PMC article.
The mechanisms responsible for the increase in hepatic DNL due to overconsumption of carbohydrate diet are less than clear; however, literatures suggest high carbohydrate diet to activate the lipogenic transcription factor carbohydrate response element-binding protein (ChR …
The mechanisms responsible for the increase in hepatic DNL due to overconsumption of carbohydrate diet are less than clear; however, …
Bax expression in benign and malignant thyroid tumours: dysregulation of wild-type P53 is associated with a high Bax and P21 expression in thyroid carcinoma.
Hermann S, Sturm I, Mrozek A, Klosterhalfen B, Hauptmann S, Dörken B, Daniel PT. Hermann S, et al. Among authors: daniel pt. Int J Cancer. 2001 Jun 15;92(6):805-11. doi: 10.1002/ijc.1284. Int J Cancer. 2001. PMID: 11351299 Free article.
Surprisingly, we observed elevated BAX levels in patients with thyroid carcinomas compared with patients with adenomas (unpaired t-test: p<0.05) or with goitres (p<0.02). This is in clear contrast to other carcinomas where BAX is frequently inactivated which correlat …
Surprisingly, we observed elevated BAX levels in patients with thyroid carcinomas compared with patients with adenomas (unpaired t-test: p&l …
Spectroscopic investigation of polystyrene surface grafting on natural rubber.
Prakanrat S, Phinyocheep P, Daniel P. Prakanrat S, et al. Among authors: daniel p. Appl Spectrosc. 2009 Feb;63(2):233-8. doi: 10.1366/000370209787391978. Appl Spectrosc. 2009. PMID: 19215654
The characteristic signals detected by Raman scattering and by attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy provide clear evidence of the PS being grafted onto the NR. The distribution of the grafted PS on the NR substrate was determine …
The characteristic signals detected by Raman scattering and by attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectros …
Detection of molecular changes induced by antibiotics in Escherichia coli using vibrational spectroscopy.
Xuan Nguyen NT, Sarter S, Hai Nguyen N, Daniel P. Xuan Nguyen NT, et al. Among authors: daniel p. Spectrochim Acta A Mol Biomol Spectrosc. 2017 Aug 5;183:395-401. doi: 10.1016/j.saa.2017.04.077. Epub 2017 Apr 27. Spectrochim Acta A Mol Biomol Spectrosc. 2017. PMID: 28463778
Regarding ciprofloxacin, an increase in nucleic acids (775, 1478, 1578cm(-1)) in Raman spectra and in protein bands (1230, 1520, 1630cm(-1)), in DNA (1080cm(-1)) in IR spectra were detected. Clear discrimination of antibiotic-treated samples compared to the control was rec …
Regarding ciprofloxacin, an increase in nucleic acids (775, 1478, 1578cm(-1)) in Raman spectra and in protein bands (1230, 1520, 1630cm(-1)) …
Bax-dependent regulation of Bak by voltage-dependent anion channel 2.
Chandra D, Choy G, Daniel PT, Tang DG. Chandra D, et al. Among authors: daniel pt. J Biol Chem. 2005 May 13;280(19):19051-61. doi: 10.1074/jbc.M501391200. Epub 2005 Mar 9. J Biol Chem. 2005. PMID: 15757910 Free article.
Using isogenic cells with defined genetic deficiencies, here we show that in response to intrinsic, extrinsic, and endoplasmic reticulum stress stimuli, HCT116 cells show clear-cut apoptotic sensitivities in the order of Bax+/Bak+ > Bax+/Bak- >> Bax-/Bak+ >> …
Using isogenic cells with defined genetic deficiencies, here we show that in response to intrinsic, extrinsic, and endoplasmic reticulum str …
Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.
Sturm I, Stephan C, Gillissen B, Siebert R, Janz M, Radetzki S, Jung K, Loening S, Dörken B, Daniel PT. Sturm I, et al. Among authors: daniel pt. Cell Death Differ. 2006 Apr;13(4):619-27. doi: 10.1038/sj.cdd.4401782. Cell Death Differ. 2006. PMID: 16322756
In detail, we show that loss of the BH3-only protein natural born killer (Nbk)/Bcl-2-interacting killer (Bik) is a common feature of clear-cell renal cell carcinoma (RCC). While strong Nbk expression is found in the renal tubuli and the epithelial lining of the glomerula, …
In detail, we show that loss of the BH3-only protein natural born killer (Nbk)/Bcl-2-interacting killer (Bik) is a common feature of clea …
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis.
Raisova M, Hossini AM, Eberle J, Riebeling C, Wieder T, Sturm I, Daniel PT, Orfanos CE, Geilen CC. Raisova M, et al. Among authors: daniel pt. J Invest Dermatol. 2001 Aug;117(2):333-40. doi: 10.1046/j.0022-202x.2001.01409.x. J Invest Dermatol. 2001. PMID: 11511312 Free article.
Low Bax expression was not a consequence of mutations in the p53 coding sequence. The Bax/Bcl-2 ratio was also in clear correlation with sensitivity to another cell death inducer, N-acetylsphingosine. ...
Low Bax expression was not a consequence of mutations in the p53 coding sequence. The Bax/Bcl-2 ratio was also in clear correlation w …
16 results