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Correlation of tumor PD-L1 expression in different tissue types and outcome of PD-1-based immunotherapy in metastatic melanoma - analysis of the DeCOG prospective multicenter cohort study ADOREG/TRIM.
Placke JM, Kimmig M, Griewank K, Herbst R, Terheyden P, Utikal J, Pföhler C, Ulrich J, Kreuter A, Mohr P, Gutzmer R, Meier F, Dippel E, Welzel J, Engel DR, Kreft S, Sucker A, Lodde G, Krefting F, Stoffels I, Klode J, Roesch A, Zimmer L, Livingstone E, Hadaschik E, Becker JC, Weichenthal M, Tasdogan A, Schadendorf D, Ugurel S. Placke JM, et al. Among authors: engel dr. EBioMedicine. 2023 Oct;96:104774. doi: 10.1016/j.ebiom.2023.104774. Epub 2023 Sep 4. EBioMedicine. 2023. PMID: 37660535 Free PMC article.
The global burden of antimicrobial resistance - urinary tract infections.
Von Vietinghoff S, Shevchuk O, Dobrindt U, Engel DR, Jorch SK, Kurts C, Miethke T, Wagenlehner F. Von Vietinghoff S, et al. Among authors: engel dr. Nephrol Dial Transplant. 2024 Mar 27;39(4):581-588. doi: 10.1093/ndt/gfad233. Nephrol Dial Transplant. 2024. PMID: 37891013
A network of trans-cortical capillaries as mainstay for blood circulation in long bones.
Grüneboom A, Hawwari I, Weidner D, Culemann S, Müller S, Henneberg S, Brenzel A, Merz S, Bornemann L, Zec K, Wuelling M, Kling L, Hasenberg M, Voortmann S, Lang S, Baum W, Ohs A, Kraff O, Quick HH, Jäger M, Landgraeber S, Dudda M, Danuser R, Stein JV, Rohde M, Gelse K, Garbe AI, Adamczyk A, Westendorf AM, Hoffmann D, Christiansen S, Engel DR, Vortkamp A, Krönke G, Herrmann M, Kamradt T, Schett G, Hasenberg A, Gunzer M. Grüneboom A, et al. Among authors: engel dr. Nat Metab. 2019 Feb;1(2):236-250. doi: 10.1038/s42255-018-0016-5. Epub 2019 Jan 21. Nat Metab. 2019. PMID: 31620676 Free PMC article.
Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections.
Subramaniam N, Bottek J, Thiebes S, Zec K, Kudla M, Soun C, de Dios Panal E, Lill JK, Pfennig A, Herrmann R, Bruderek K, Rahmann S, Brandau S, Johansson P, Reinhardt HC, Dürig J, Seiffert M, Bracht T, Sitek B, Engel DR. Subramaniam N, et al. Among authors: engel dr. Blood Adv. 2021 Mar 9;5(5):1259-1272. doi: 10.1182/bloodadvances.2020002949. Blood Adv. 2021. PMID: 33651101 Free PMC article.
Digital Quantification of Tumor PD-L1 Predicts Outcome of PD-1-Based Immune Checkpoint Therapy in Metastatic Melanoma.
Placke JM, Soun C, Bottek J, Herbst R, Terheyden P, Utikal J, Pföhler C, Ulrich J, Kreuter A, Pfeiffer C, Mohr P, Gutzmer R, Meier F, Dippel E, Weichenthal M, Zimmer L, Livingstone E, Becker JC, Lodde G, Sucker A, Griewank K, Horn S, Hadaschik E, Roesch A, Schadendorf D, Engel DR, Ugurel S. Placke JM, et al. Among authors: engel dr. Front Oncol. 2021 Sep 21;11:741993. doi: 10.3389/fonc.2021.741993. eCollection 2021. Front Oncol. 2021. PMID: 34621681 Free PMC article.
The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion.
Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck AK, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth SG, Zipp F, Hemmer B, Engel DR, Roth J, Kuhlmann T, Wiendl H, Klotz L. Hucke S, et al. Among authors: engel dr. Acta Neuropathol. 2016 Sep;132(3):413-31. doi: 10.1007/s00401-016-1593-6. Epub 2016 Jul 6. Acta Neuropathol. 2016. PMID: 27383204
Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus.
Pohl JM, Gutweiler S, Thiebes S, Volke JK, Klein-Hitpass L, Zwanziger D, Gunzer M, Jung S, Agace WW, Kurts C, Engel DR. Pohl JM, et al. Among authors: engel dr. Gut. 2017 Dec;66(12):2110-2120. doi: 10.1136/gutjnl-2017-313856. Epub 2017 Jun 14. Gut. 2017. PMID: 28615301 Free PMC article.