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Page 1
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Among authors: croker de. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
Derivation of ligands for the complement C3a receptor from the C-terminus of C5a.
Halai R, Bellows-Peterson ML, Branchett W, Smadbeck J, Kieslich CA, Croker DE, Cooper MA, Morikis D, Woodruff TM, Floudas CA, Monk PN. Halai R, et al. Among authors: croker de. Eur J Pharmacol. 2014 Dec 15;745:176-81. doi: 10.1016/j.ejphar.2014.10.041. Epub 2014 Oct 30. Eur J Pharmacol. 2014. PMID: 25446428 Free PMC article.
Allosteric alpha 1-adrenoreceptor antagonism by the conopeptide rho-TIA.
Sharpe IA, Thomas L, Loughnan M, Motin L, Palant E, Croker DE, Alewood D, Chen S, Graham RM, Alewood PF, Adams DJ, Lewis RJ. Sharpe IA, et al. Among authors: croker de. J Biol Chem. 2003 Sep 5;278(36):34451-7. doi: 10.1074/jbc.M305410200. Epub 2003 Jun 24. J Biol Chem. 2003. PMID: 12824165 Free article.