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New derivatives from dehydrodieugenol B and its methyl ether displayed high anti-Trypanosoma cruzi activity and cause depolarization of the plasma membrane and collapse the mitochondrial membrane potential.
Galhardo TS, Ueno AK, Costa-Silva TA, Tempone AG, Carvalho WA, Fischmeister C, Bruneau C, Mandelli D, Lago JHG. Galhardo TS, et al. Among authors: mandelli d. Chem Biol Interact. 2022 Oct 1;366:110129. doi: 10.1016/j.cbi.2022.110129. Epub 2022 Sep 5. Chem Biol Interact. 2022. PMID: 36067825 Free article.