Bioactivities from marine algae of the genus Gracilaria

Int J Mol Sci. 2011;12(7):4550-73. doi: 10.3390/ijms12074550. Epub 2011 Jul 15.

Abstract

Seaweeds are an important source of bioactive metabolites for the pharmaceutical industry in drug development. Many of these compounds are used to treat diseases like cancer, acquired immune-deficiency syndrome (AIDS), inflammation, pain, arthritis, as well as viral, bacterial, and fungal infections. This paper offers a survey of the literature for Gracilaria algae extracts with biological activity, and identifies avenues for future research. Nineteen species of this genus that were tested for antibacterial, antiviral, antifungal, antihypertensive, cytotoxic, spermicidal, embriotoxic, and anti-inflammatory activities are cited from the 121 references consulted.

Keywords: Gracilaria; biological activity; macroalgae; natural product; review; seaweed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Anti-Inflammatory Agents / chemistry
  • Anti-Inflammatory Agents / pharmacology
  • Anticonvulsants / chemistry
  • Anticonvulsants / pharmacology
  • Bacteria / drug effects
  • Cell Survival / drug effects
  • DNA Viruses / drug effects
  • Fungi / drug effects
  • Gracilaria / chemistry
  • Gracilaria / metabolism*
  • Humans
  • Nervous System / drug effects
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Platelet Aggregation / drug effects
  • RNA Viruses / drug effects

Substances

  • Anti-Infective Agents
  • Anti-Inflammatory Agents
  • Anticonvulsants
  • Plant Extracts