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Page 1
Omega-3 Polyunsaturated Fatty Acid Derived Lipid Mediators and their Application in Drug Discovery.
Curr Med Chem. 2020;27(10):1670-1689. doi: 10.2174/0929867325666180927100120.
Curr Med Chem. 2020.
PMID: 30259807
Review.
Anti-tumor activities of lipids and lipid analogues and their development as potential anticancer drugs.
Murray M, Hraiki A, Bebawy M, Pazderka C, Rawling T.
Murray M, et al. Among authors: pazderka c.
Pharmacol Ther. 2015 Jun;150:109-28. doi: 10.1016/j.pharmthera.2015.01.008. Epub 2015 Jan 17.
Pharmacol Ther. 2015.
PMID: 25603423
Review.
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Nanoemulsion-Enabled Oral Delivery of Novel Anticancer ω-3 Fatty Acid Derivatives.
Garrastazu Pereira G, Rawling T, Pozzoli M, Pazderka C, Chen Y, Dunstan CR, Murray M, Sonvico F.
Garrastazu Pereira G, et al. Among authors: pazderka c.
Nanomaterials (Basel). 2018 Oct 13;8(10):825. doi: 10.3390/nano8100825.
Nanomaterials (Basel). 2018.
PMID: 30322115
Free PMC article.
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Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids.
Rahman MK, Umashankar B, Choucair H, Pazderka C, Bourget K, Chen Y, Dunstan CR, Rawling T, Murray M.
Rahman MK, et al. Among authors: pazderka c.
Eur J Pharmacol. 2023 Jan 15;939:175470. doi: 10.1016/j.ejphar.2022.175470. Epub 2022 Dec 18.
Eur J Pharmacol. 2023.
PMID: 36543287
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Aryl urea substituted fatty acids: a new class of protonophoric mitochondrial uncoupler that utilises a synthetic anion transporter.
Rawling T, MacDermott-Opeskin H, Roseblade A, Pazderka C, Clarke C, Bourget K, Wu X, Lewis W, Noble B, Gale PA, O'Mara ML, Cranfield C, Murray M.
Rawling T, et al. Among authors: pazderka c.
Chem Sci. 2020 Aug 19;11(47):12677-12685. doi: 10.1039/d0sc02777d.
Chem Sci. 2020.
PMID: 34094462
Free PMC article.
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Aryl-urea fatty acids that activate the p38 MAP kinase and down-regulate multiple cyclins decrease the viability of MDA-MB-231 breast cancer cells.
Al-Zubaidi Y, Pazderka C, Koolaji N, Rahman MK, Choucair H, Umashankar B, Bourget K, Chen Y, Rawling T, Murray M.
Al-Zubaidi Y, et al. Among authors: pazderka c.
Eur J Pharm Sci. 2019 Mar 1;129:87-98. doi: 10.1016/j.ejps.2018.12.015. Epub 2018 Dec 29.
Eur J Pharm Sci. 2019.
PMID: 30597206
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