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METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.
Vaid R, Thombare K, Mendez A, Burgos-Panadero R, Djos A, Jachimowicz D, Lundberg KI, Bartenhagen C, Kumar N, Tümmler C, Sihlbom C, Fransson S, Johnsen JI, Kogner P, Martinsson T, Fischer M, Mondal T. Vaid R, et al. Among authors: tummler c. Nucleic Acids Res. 2024 Mar 21;52(5):2648-2671. doi: 10.1093/nar/gkad1242. Nucleic Acids Res. 2024. PMID: 38180812 Free PMC article.
DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.
Olsen TK, Dyberg C, Embaie BT, Alchahin A, Milosevic J, Ding J, Otte J, Tümmler C, Hed Myrberg I, Westerhout EM, Koster J, Versteeg R, Ding HF, Kogner P, Johnsen JI, Sykes DB, Baryawno N. Olsen TK, et al. Among authors: tummler c. JCI Insight. 2022 Aug 9;7(17):e153836. doi: 10.1172/jci.insight.153836. JCI Insight. 2022. PMID: 35943801 Free PMC article.