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Page 1
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Costi R, Di Santo R. Saccoliti F, et al. Among authors: calvet cm. Eur J Med Chem. 2018 Aug 5;156:53-60. doi: 10.1016/j.ejmech.2018.06.063. Epub 2018 Jun 28. Eur J Med Chem. 2018. PMID: 30006174
Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi.
Lechuga GC, Borges JC, Calvet CM, de Araújo HP, Zuma AA, do Nascimento SB, Motta MCM, Bernardino AMR, Pereira MCS, Bourguignon SC. Lechuga GC, et al. Among authors: calvet cm. Int J Parasitol Drugs Drug Resist. 2016 Dec;6(3):154-164. doi: 10.1016/j.ijpddr.2016.07.001. Epub 2016 Jul 14. Int J Parasitol Drugs Drug Resist. 2016. PMID: 27490082 Free PMC article.
Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast.
Ottilie S, Goldgof GM, Calvet CM, Jennings GK, LaMonte G, Schenken J, Vigil E, Kumar P, McCall LI, Lopes ES, Gunawan F, Yang J, Suzuki Y, Siqueira-Neto JL, McKerrow JH, Amaro RE, Podust LM, Durrant JD, Winzeler EA. Ottilie S, et al. Among authors: calvet cm. ACS Chem Biol. 2017 Feb 17;12(2):422-434. doi: 10.1021/acschembio.6b01037. Epub 2016 Dec 23. ACS Chem Biol. 2017. PMID: 27977118 Free PMC article.
Trypanosoma cruzi infection of human induced pluripotent stem cell-derived cardiomyocytes: an in vitro model for drug screening for Chagas disease.
da Silva Lara L, Andrade-Lima L, Magalhães Calvet C, Borsoi J, Lopes Alberto Duque T, Henriques-Pons A, Souza Pereira MC, Veiga Pereira L. da Silva Lara L, et al. Among authors: magalhaes calvet c. Microbes Infect. 2018 May;20(5):312-316. doi: 10.1016/j.micinf.2018.03.002. Epub 2018 Mar 22. Microbes Infect. 2018. PMID: 29577969 Free article.
4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection.
Calvet CM, Choi JY, Thomas D, Suzuki B, Hirata K, Lostracco-Johnson S, de Mesquita LB, Nogueira A, Meuser-Batista M, Silva TA, Siqueira-Neto JL, Roush WR, de Souza Pereira MC, McKerrow JH, Podust LM. Calvet CM, et al. PLoS Negl Trop Dis. 2017 Dec 27;11(12):e0006132. doi: 10.1371/journal.pntd.0006132. eCollection 2017 Dec. PLoS Negl Trop Dis. 2017. PMID: 29281643 Free PMC article.