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Recombinant botulinum neurotoxin serotype A1 in vivo characterization.
Périer C, Martin V, Cornet S, Favre-Guilmard C, Rocher MN, Bindler J, Wagner S, Andriambeloson E, Rudkin B, Marty R, Vignaud A, Beard M, Lezmi S, Kalinichev M. Périer C, et al. Pharmacol Res Perspect. 2021 Oct;9(5):e00857. doi: 10.1002/prp2.857. Pharmacol Res Perspect. 2021. PMID: 34632725 Free PMC article.
Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.
Elliott M, Favre-Guilmard C, Liu SM, Maignel J, Masuyer G, Beard M, Boone C, Carré D, Kalinichev M, Lezmi S, Mir I, Nicoleau C, Palan S, Perier C, Raban E, Zhang S, Dong M, Stenmark P, Krupp J. Elliott M, et al. Among authors: perier c. Sci Adv. 2019 Jan 16;5(1):eaau7196. doi: 10.1126/sciadv.aau7196. eCollection 2019 Jan. Sci Adv. 2019. PMID: 30746458 Free PMC article.
A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo.
Donald S, Elliott M, Gray B, Hornby F, Lewandowska A, Marlin S, Favre-Guilmard C, Périer C, Cornet S, Kalinichev M, Krupp J, Fonfria E. Donald S, et al. Among authors: perier c. Pharmacol Res Perspect. 2018 Nov 22;6(6):e00446. doi: 10.1002/prp2.446. eCollection 2018 Dec. Pharmacol Res Perspect. 2018. PMID: 30519475 Free PMC article.