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Page 1
Structure-Activity Relationship for Thiirane-Based Gelatinase Inhibitors.
Lee M, Ikejiri M, Klimpel D, Toth M, Espahbodi M, Hesek D, Forbes C, Kumarasiri M, Noll BC, Chang M, Mobashery S. Lee M, et al. Among authors: forbes c. ACS Med Chem Lett. 2012 Jun 14;3(6):490-495. doi: 10.1021/ml300050b. Epub 2012 May 2. ACS Med Chem Lett. 2012. PMID: 22737278 Free PMC article.
Metabolism of a highly selective gelatinase inhibitor generates active metabolite.
Lee M, Villegas-Estrada A, Celenza G, Boggess B, Toth M, Kreitinger G, Forbes C, Fridman R, Mobashery S, Chang M. Lee M, et al. Among authors: forbes c. Chem Biol Drug Des. 2007 Nov;70(5):371-82. doi: 10.1111/j.1747-0285.2007.00577.x. Epub 2007 Oct 10. Chem Biol Drug Des. 2007. PMID: 17927722
Unusually low barrier to carbamate C-N rotation.
Deetz MJ, Forbes CC, Jonas M, Malerich JP, Smith BD, Wiest O. Deetz MJ, et al. Among authors: forbes cc. J Org Chem. 2002 May 31;67(11):3949-52. doi: 10.1021/jo025554u. J Org Chem. 2002. PMID: 12027723