Anti-infective vaccination strategies in patients with hematologic malignancies or solid tumors-Guideline of the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO)

Ann Oncol. 2018 Jun 1;29(6):1354-1365. doi: 10.1093/annonc/mdy117.

Abstract

Infectious complications are a significant cause of morbidity and mortality in patients with malignancies specifically when receiving anticancer treatments. Prevention of infection through vaccines is an important aspect of clinical care of cancer patients. Immunocompromising effects of the underlying disease as well as of antineoplastic therapies need to be considered when devising vaccination strategies. This guideline provides clinical recommendations on vaccine use in cancer patients including autologous stem cell transplant recipients, while allogeneic stem cell transplantation is subject of a separate guideline. The document was prepared by the Infectious Diseases Working Party (AGIHO) of the German Society for Hematology and Medical Oncology (DGHO) by reviewing currently available data and applying evidence-based medicine criteria.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Infective Agents / therapeutic use*
  • Communicable Diseases / drug therapy*
  • Communicable Diseases / etiology
  • Hematologic Neoplasms / therapy*
  • Humans
  • Neoplasms / therapy*
  • Practice Guidelines as Topic / standards*
  • Prognosis
  • Stem Cell Transplantation / adverse effects*
  • Vaccination / standards*

Substances

  • Anti-Infective Agents