Christian Gege - Search Results

Year	Number of Results
1999	1
2002	3
2003	2
2004	1
2005	1
2006	1
2007	1
2008	2
2009	4
2011	2
2012	1
2013	1
2014	2
2015	1
2016	3
2017	1
2018	1
2019	1
2020	3
2021	4
2022	1
2023	3
2024	1

1

Development of a Potent Nurr1 Agonist Tool for In Vivo Applications.

Vietor J, Gege C, Stiller T, Busch R, Schallmayer E, Kohlhof H, Höfner G, Pabel J, Marschner JA, Merk D. Vietor J, et al. Among authors: gege c. J Med Chem. 2023 May 11;66(9):6391-6402. doi: 10.1021/acs.jmedchem.3c00415. Epub 2023 Apr 26. J Med Chem. 2023. PMID: 37127285 Free PMC article.

2

Nonsteroidal FXR Ligands: Current Status and Clinical Applications.

Gege C, Hambruch E, Hambruch N, Kinzel O, Kremoser C. Gege C, et al. Handb Exp Pharmacol. 2019;256:167-205. doi: 10.1007/164_2019_232. Handb Exp Pharmacol. 2019. PMID: 31197565 Review.

3

Retinoic acid-related orphan receptor gamma t (RORγt) inverse agonists/antagonists for the treatment of inflammatory diseases - where are we presently?

Gege C. Gege C. Expert Opin Drug Discov. 2021 Dec;16(12):1517-1535. doi: 10.1080/17460441.2021.1948833. Epub 2021 Jul 7. Expert Opin Drug Discov. 2021. PMID: 34192992 Review.

4

Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities.

Gege C, Kinzel O, Steeneck C, Schulz A, Kremoser C. Gege C, et al. Curr Top Med Chem. 2014;14(19):2143-58. doi: 10.2174/1568026614666141112094430. Curr Top Med Chem. 2014. PMID: 25388536 Review.

5

Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt.

Gege C, Albers M, Kinzel O, Kleymann G, Schlüter T, Steeneck C, Hoffmann T, Xue X, Cummings MD, Spurlino J, Milligan C, Fourie AM, Edwards JP, Leonard K, Coe K, Scott B, Pippel D, Goldberg SD. Gege C, et al. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127205. doi: 10.1016/j.bmcl.2020.127205. Epub 2020 Apr 21. Bioorg Med Chem Lett. 2020. PMID: 32336498

6

Interplay of Trans- and Cis-Interactions of Glycolipids in Membrane Adhesion.

Kav B, Demé B, Gege C, Tanaka M, Schneck E, Weikl TR. Kav B, et al. Among authors: gege c. Front Mol Biosci. 2021 Nov 19;8:754654. doi: 10.3389/fmolb.2021.754654. eCollection 2021. Front Mol Biosci. 2021. PMID: 34869588 Free PMC article.

7

Intermittent therapy with helicase-primase inhibitor IM-250 efficiently controls recurrent herpes disease and reduces reactivation of latent HSV.

Bernstein DI, Sawtell NM, Bravo FJ, Dixon DA, Gege C, Kleymann G. Bernstein DI, et al. Among authors: gege c. Antiviral Res. 2023 Nov;219:105733. doi: 10.1016/j.antiviral.2023.105733. Epub 2023 Oct 18. Antiviral Res. 2023. PMID: 37858763 Free article.

8

Helicase-primase inhibitors from Medshine Discovery Inc. (WO2018/127207 and WO2020/007355) for the treatment of herpes simplex virus infections - structure proposal for Phaeno Therapeutics drug candidate HN0037.

Gege C, Kleymann G. Gege C, et al. Expert Opin Ther Pat. 2022 Sep;32(9):933-937. doi: 10.1080/13543776.2022.2113873. Epub 2022 Aug 19. Expert Opin Ther Pat. 2022. PMID: 35965439

9

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction.

Mayr F, Möller G, Garscha U, Fischer J, Rodríguez Castaño P, Inderbinen SG, Temml V, Waltenberger B, Schwaiger S, Hartmann RW, Gege C, Martens S, Odermatt A, Pandey AV, Werz O, Adamski J, Stuppner H, Schuster D. Mayr F, et al. Among authors: gege c. Int J Mol Sci. 2020 Sep 26;21(19):7102. doi: 10.3390/ijms21197102. Int J Mol Sci. 2020. PMID: 32993084 Free PMC article.

10

A helicase-primase drug candidate with sufficient target tissue exposure affects latent neural herpes simplex virus infections.

Gege C, Bravo FJ, Uhlig N, Hagmaier T, Schmachtenberg R, Elis J, Burger-Kentischer A, Finkelmeier D, Hamprecht K, Grunwald T, Bernstein DI, Kleymann G. Gege C, et al. Sci Transl Med. 2021 Jun 16;13(598):eabf8668. doi: 10.1126/scitranslmed.abf8668. Sci Transl Med. 2021. PMID: 34135112

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