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Page 1
Discovery and Optimization of a Compound Series Active against Trypanosoma cruzi, the Causative Agent of Chagas Disease.
Harrison JR, Sarkar S, Hampton S, Riley J, Stojanovski L, Sahlberg C, Appelqvist P, Erath J, Mathan V, Rodriguez A, Kaiser M, Pacanowska DG, Read KD, Johansson NG, Gilbert IH. Harrison JR, et al. Among authors: sahlberg c. J Med Chem. 2020 Mar 26;63(6):3066-3089. doi: 10.1021/acs.jmedchem.9b01852. Epub 2020 Mar 5. J Med Chem. 2020. PMID: 32134269
Design and synthesis of potent macrocyclic renin inhibitors.
Sund C, Belda O, Wiktelius D, Sahlberg C, Vrang L, Sedig S, Hamelink E, Henderson I, Agback T, Jansson K, Borkakoti N, Derbyshire D, Eneroth A, Samuelsson B. Sund C, et al. Among authors: sahlberg c. Bioorg Med Chem Lett. 2011 Jan 1;21(1):358-62. doi: 10.1016/j.bmcl.2010.10.140. Epub 2010 Nov 5. Bioorg Med Chem Lett. 2011. PMID: 21112780
Aliskiren displays long-lasting interactions with human renin.
Gossas T, Vrang L, Henderson I, Sedig S, Sahlberg C, Lindström E, Danielson UH. Gossas T, et al. Among authors: sahlberg c. Naunyn Schmiedebergs Arch Pharmacol. 2012 Feb;385(2):219-24. doi: 10.1007/s00210-011-0718-7. Epub 2011 Dec 23. Naunyn Schmiedebergs Arch Pharmacol. 2012. PMID: 22193701