Cobalt Complexes as Antiviral and Antibacterial Agents

Eddie L Chang; Christa Simmers; D Andrew Knight

doi:10.3390/ph3061711

Cobalt Complexes as Antiviral and Antibacterial Agents

Pharmaceuticals (Basel). 2010 May 26;3(6):1711-1728. doi: 10.3390/ph3061711.

Authors

Eddie L Chang¹, Christa Simmers², D Andrew Knight³

Affiliations

¹ Center for Bio/Molecular Science and Engineering, Naval Research Laboratory, 4555 Overlook Avenue S.W., Washington, DC 20375, USA. eddie.chang@nrl.navy.mil.
² Chemistry Department, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901, USA. simmersc2008@my.fit.edu.
³ Chemistry Department, Florida Institute of Technology, 150 West University Boulevard, Melbourne, FL 32901, USA. aknight@fit.edu.

Abstract

Metal ion complexes are playing an increasing role in the development of antimicrobials. We review here the antimicrobial properties of cobalt coordination complexes in oxidation state 3+. In addition to reviewing the cobalt complexes containing polydentate donor ligands, we also focus on the antimicrobial activity of the homoleptic [Co(NH₃)₆]³⁺ ion.

Keywords: antibacterial; antiviral; cobalt.

Publication types

Review