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Massively multiplexed nucleic acid detection with Cas13.
Ackerman CM, Myhrvold C, Thakku SG, Freije CA, Metsky HC, Yang DK, Ye SH, Boehm CK, Kosoko-Thoroddsen TF, Kehe J, Nguyen TG, Carter A, Kulesa A, Barnes JR, Dugan VG, Hung DT, Blainey PC, Sabeti PC. Ackerman CM, et al. Among authors: boehm ck. Nature. 2020 Jun;582(7811):277-282. doi: 10.1038/s41586-020-2279-8. Epub 2020 Apr 29. Nature. 2020. PMID: 32349121 Free PMC article.
The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response.
Botti-Lodovico Y, Nair P, Nosamiefan D, Stremlau M, Schaffner S, Agignoae SV, Aiyepada JO, Ajogbasile FV, Akpede GO, Alhasan F, Andersen KG, Asogun DA, Ayodeji OO, Badiane AS, Barnes K, Bauer MR, Bell-Kareem A, Benard ME, Benevolence EO, Blessing O, Boehm CK, Boisen ML, Bond NG, Branco LM, Butts MJ, Carter A, Colubri A, Deme AB, DeRuff KC, Diédhiou Y, Edamhande AP, Elhamoumi S, Engel EJ, Eromon P, Fallah M, Folarin OA, Fry B, Garry R, Gaye A, Gbakie M, Gevao SM, Gionet G, Gladden-Young A, Goba A, Gomis JF, Happi AN, Houghton M, Ihekwuazu C, Iruolagbe CO, Jackson J, Jalloh S, Johnson J, Kanneh L, Kayode A, Kemball M, Kingsley OC, Koroma V, Kotliar D, Mehta S, Metsky HC, Michael A, Mirhashemi ME, Modjarrad K, Momoh M, Myhrvold CA, Naregose OG, Ndiaye T, Ndiaye M, Ndiaye A, Normandin E, Odia I, Oguzie JU, Okogbenin SA, Okokhere PO, Okolie J, Olawoye IB, Olumade TJ, Oluniyi PE, Omoregie O, Park DJ, Paye MF, Petros B, Philippakis AA, Priscilla A, Ricks A, Rimoin A, Sandi JD, Schieffelin JS, Schreiber M, Seck MC, Siddiqui S, Siddle K, Smither AR, Sy M, Sy N, Tomkins-Tinch CH, Tomori O, Ugwu C, Uwanibe JN, Uyigue EA, Victoria DI, Vinzé A, Vodzak ME, Welch N, Wurie HI, Zoumarou D, … See abstract for full author list ➔ Botti-Lodovico Y, et al. Among authors: boehm ck. Viruses. 2021 Aug 13;13(8):1605. doi: 10.3390/v13081605. Viruses. 2021. PMID: 34452470 Free PMC article.
Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2.
Arizti-Sanz J, Freije CA, Stanton AC, Petros BA, Boehm CK, Siddiqui S, Shaw BM, Adams G, Kosoko-Thoroddsen TF, Kemball ME, Uwanibe JN, Ajogbasile FV, Eromon PE, Gross R, Wronka L, Caviness K, Hensley LE, Bergman NH, MacInnis BL, Happi CT, Lemieux JE, Sabeti PC, Myhrvold C. Arizti-Sanz J, et al. Among authors: boehm ck. Nat Commun. 2020 Nov 20;11(1):5921. doi: 10.1038/s41467-020-19097-x. Nat Commun. 2020. PMID: 33219225 Free PMC article.
Simplified Cas13-based assays for the fast identification of SARS-CoV-2 and its variants.
Arizti-Sanz J, Bradley A, Zhang YB, Boehm CK, Freije CA, Grunberg ME, Kosoko-Thoroddsen TF, Welch NL, Pillai PP, Mantena S, Kim G, Uwanibe JN, John OG, Eromon PE, Kocher G, Gross R, Lee JS, Hensley LE, MacInnis BL, Johnson J, Springer M, Happi CT, Sabeti PC, Myhrvold C. Arizti-Sanz J, et al. Among authors: boehm ck. Nat Biomed Eng. 2022 Aug;6(8):932-943. doi: 10.1038/s41551-022-00889-z. Epub 2022 May 30. Nat Biomed Eng. 2022. PMID: 35637389 Free PMC article.
Equipment-free detection of SARS-CoV-2 and Variants of Concern using Cas13.
Arizti-Sanz J, Bradley A, Zhang YB, Boehm CK, Freije CA, Grunberg ME, Kosoko-Thoroddsen TF, Welch NL, Pillai PP, Mantena S, Kim G, Uwanibe JN, John OG, Eromon PE, Kocher G, Gross R, Lee JS, Hensley LE, Happi CT, Johnson J, Sabeti PC, Myhrvold C. Arizti-Sanz J, et al. Among authors: boehm ck. medRxiv [Preprint]. 2021 Nov 2:2021.11.01.21265764. doi: 10.1101/2021.11.01.21265764. medRxiv. 2021. PMID: 34751276 Free PMC article. Updated. Preprint.
Programmable Inhibition and Detection of RNA Viruses Using Cas13.
Freije CA, Myhrvold C, Boehm CK, Lin AE, Welch NL, Carter A, Metsky HC, Luo CY, Abudayyeh OO, Gootenberg JS, Yozwiak NL, Zhang F, Sabeti PC. Freije CA, et al. Among authors: boehm ck. Mol Cell. 2019 Dec 5;76(5):826-837.e11. doi: 10.1016/j.molcel.2019.09.013. Epub 2019 Oct 10. Mol Cell. 2019. PMID: 31607545 Free PMC article.
Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2.
Arizti-Sanz J, Freije CA, Stanton AC, Boehm CK, Petros BA, Siddiqui S, Shaw BM, Adams G, Kosoko-Thoroddsen TF, Kemball ME, Gross R, Wronka L, Caviness K, Hensley LE, Bergman NH, MacInnis BL, Lemieux JE, Sabeti PC, Myhrvold C. Arizti-Sanz J, et al. Among authors: boehm ck. bioRxiv [Preprint]. 2020 May 28:2020.05.28.119131. doi: 10.1101/2020.05.28.119131. bioRxiv. 2020. PMID: 32511415 Free PMC article. Updated. Preprint.
Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time.
Barnes KG, Lachenauer AE, Nitido A, Siddiqui S, Gross R, Beitzel B, Siddle KJ, Freije CA, Dighero-Kemp B, Mehta SB, Carter A, Uwanibe J, Ajogbasile F, Olumade T, Odia I, Sandi JD, Momoh M, Metsky HC, Boehm CK, Lin AE, Kemball M, Park DJ, Branco L, Boisen M, Sullivan B, Amare MF, Tiamiyu AB, Parker ZF, Iroezindu M, Grant DS, Modjarrad K, Myhrvold C, Garry RF, Palacios G, Hensley LE, Schaffner SF, Happi CT, Colubri A, Sabeti PC. Barnes KG, et al. Among authors: boehm ck. Nat Commun. 2020 Aug 17;11(1):4131. doi: 10.1038/s41467-020-17994-9. Nat Commun. 2020. PMID: 32807807 Free PMC article.
Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions.
Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilieş I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Sîrbulescu RF, et al. Among authors: boehm ck. Wound Repair Regen. 2017 Sep;25(5):774-791. doi: 10.1111/wrr.12584. Epub 2017 Oct 17. Wound Repair Regen. 2017. PMID: 28922523 Free PMC article.