Synthesis and characterization of polyethylene glycol (PEG) coated Fe3O4 nanoparticles by chemical co-precipitation method for biomedical applications

Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jan 25:135:536-9. doi: 10.1016/j.saa.2014.07.059. Epub 2014 Jul 27.

Abstract

Polyethylene glycol (PEG) coated Fe3O4 nanoparticles were synthesized by chemical co-precipitation method. With polyethylene glycol (PEG) as a stabilizer and dispersant. The X-ray diffraction and selected area electron diffraction (SAED) results show that the cubic inverse spinel structure of pure phase polycrystalline Fe3O4 was obtained. The scanning electron microscopy (SEM) and field emission transmission electron microscopy (FE-TEM) results exhibited that the resulted Fe3O4 nanoparticles were roughly spherical in shape with narrow size distribution and homogenous shape. Fourier transform infrared spectroscopy (FT-IR) results suggested that PEG indicated with Fe3O4 via its carbonyl groups. Results of vibrating sample magnetometer (VSM) indicated that the prepared Fe3O4 nanoparticles exhibit superparamagnetic behavior and high saturation magnetization at room temperature. Such Fe3O4 nanoparticles with favorable size and tunable magnetic properties are promising biomedical applications.

Keywords: Biomedical; Fe(3)O(4); Magnetite; Nanoparticle; Polyethylene glycol; Superparamagnetism.

MeSH terms

  • Biomedical Technology / methods*
  • Chemical Precipitation*
  • Ferrosoferric Oxide / chemical synthesis*
  • Ferrosoferric Oxide / chemistry
  • Magnetic Phenomena
  • Nanoparticles / chemistry*
  • Nanoparticles / ultrastructure
  • Polyethylene Glycols / chemical synthesis*
  • Polyethylene Glycols / chemistry
  • Spectroscopy, Fourier Transform Infrared
  • X-Ray Diffraction

Substances

  • Polyethylene Glycols
  • Ferrosoferric Oxide