A de novo centric fission of chromosome 11 in a patient with recurrent miscarriages

Sung Han Shim; Cheol-Hoon Lee; Ji-Yeon Lee; Eun-Sim Shin; Jee Hong Kyhm; Moon-Il Park; Sung-Ro Chung; Youl-Hee Cho

doi:10.3346/jkms.2007.22.1.146

A de novo centric fission of chromosome 11 in a patient with recurrent miscarriages

J Korean Med Sci. 2007 Feb;22(1):146-8. doi: 10.3346/jkms.2007.22.1.146.

Authors

Sung Han Shim¹, Cheol-Hoon Lee, Ji-Yeon Lee, Eun-Sim Shin, Jee Hong Kyhm, Moon-Il Park, Sung-Ro Chung, Youl-Hee Cho

Affiliation

¹ Department of Medical Genetics, College of Medicine, Hanyang University, Seoul, Korea.

Abstract

We report on a de novo centric fission of chromosome 11 in a healthy female referred for chromosome analysis due to recurrent miscarriages. Both fission products were mitotically stable. This centric fission of chromosome 11 appears to have no clinical significance for this patient other than recurrent miscarriages.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Abortion, Habitual / genetics*
Adult
Chromosome Aberrations*
Chromosomes, Human, Pair 11*
Female
Humans