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Showing results for charlotte virion
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Norovirus assembly and stability.
Pogan R, Dülfer J, Uetrecht C. Pogan R, et al. Curr Opin Virol. 2018 Aug;31:59-65. doi: 10.1016/j.coviro.2018.05.003. Epub 2018 May 30. Curr Opin Virol. 2018. PMID: 29857940 Free article. Review.
Particle stability is of special interest as transmission occurs via the faecal-oral route and virions are able to persist in the environment. Studies on norovirus capsid assembly and disassembly rely mainly on norovirus-like particles. ...
Particle stability is of special interest as transmission occurs via the faecal-oral route and virions are able to persist in the env …
Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients With Mild to Moderate COVID-19: A Randomized Clinical Trial.
Naggie S, Boulware DR, Lindsell CJ, Stewart TG, Gentile N, Collins S, McCarthy MW, Jayaweera D, Castro M, Sulkowski M, McTigue K, Thicklin F, Felker GM, Ginde AA, Bramante CT, Slandzicki AJ, Gabriel A, Shah NS, Lenert LA, Dunsmore SE, Adam SJ, DeLong A, Hanna G, Remaly A, Wilder R, Wilson S, Shenkman E, Hernandez AF; Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-6) Study Group and Investigators. Naggie S, et al. JAMA. 2022 Oct 25;328(16):1595-1603. doi: 10.1001/jama.2022.18590. JAMA. 2022. PMID: 36269852 Free PMC article. Clinical Trial.
Structural mass spectrometry goes viral.
Dülfer J, Kadek A, Kopicki JD, Krichel B, Uetrecht C. Dülfer J, et al. Adv Virus Res. 2019;105:189-238. doi: 10.1016/bs.aivir.2019.07.003. Epub 2019 Aug 27. Adv Virus Res. 2019. PMID: 31522705
Native MS allows transferring viral proteins, complexes and capsids into the gas phase and has broken boundaries to overcome size limitations, so that now even the analysis of intact virions is possible. Different MS approaches not only inform about size, stability, intera …
Native MS allows transferring viral proteins, complexes and capsids into the gas phase and has broken boundaries to overcome size limitation …
Coherent diffractive imaging of proteins and viral capsids: simulating MS SPIDOC.
Kierspel T, Kadek A, Barran P, Bellina B, Bijedic A, Brodmerkel MN, Commandeur J, Caleman C, Damjanović T, Dawod I, De Santis E, Lekkas A, Lorenzen K, Morillo LL, Mandl T, Marklund EG, Papanastasiou D, Ramakers LAI, Schweikhard L, Simke F, Sinelnikova A, Smyrnakis A, Timneanu N, Uetrecht C; MS SPIDOC Consortium. Kierspel T, et al. Anal Bioanal Chem. 2023 Jul;415(18):4209-4220. doi: 10.1007/s00216-023-04658-y. Epub 2023 Apr 4. Anal Bioanal Chem. 2023. PMID: 37014373 Free PMC article.
Analysis of virion associated host proteins in vesicular stomatitis virus using a proteomics approach.
Moerdyk-Schauwecker M, Hwang SI, Grdzelishvili VZ. Moerdyk-Schauwecker M, et al. Virol J. 2009 Oct 12;6:166. doi: 10.1186/1743-422X-6-166. Virol J. 2009. PMID: 19821998 Free PMC article.
Although several cellular proteins have been previously shown to be incorporated into VSV virions, no systematic study has been done to reveal the host protein composition for virions of VSV or any other member of Mononegavirales. ...We have successfully confirmed t …
Although several cellular proteins have been previously shown to be incorporated into VSV virions, no systematic study has been done …
efam: an expanded, metaproteome-supported HMM profile database of viral protein families.
Zayed AA, Lücking D, Mohssen M, Cronin D, Bolduc B, Gregory AC, Hargreaves KR, Piehowski PD, White Iii RA, Huang EL, Adkins JN, Roux S, Moraru C, Sullivan MB. Zayed AA, et al. Bioinformatics. 2021 Nov 18;37(22):4202-4208. doi: 10.1093/bioinformatics/btab451. Bioinformatics. 2021. PMID: 34132786 Free PMC article.
Additionally, to help elucidate lesser-known viral protein functions, we annotated the profiles using multiple databases from the DRAM pipeline and virion-associated metaproteomic data, which doubled the number of annotations obtainable by standard, single-database annotat …
Additionally, to help elucidate lesser-known viral protein functions, we annotated the profiles using multiple databases from the DRAM pipel …
Identification of sendai virus L protein amino acid residues affecting viral mRNA cap methylation.
Murphy AM, Grdzelishvili VZ. Murphy AM, et al. J Virol. 2009 Feb;83(4):1669-81. doi: 10.1128/JVI.01438-08. Epub 2008 Dec 3. J Virol. 2009. PMID: 19052078 Free PMC article.
Using a reverse genetics approach, these mutations were introduced into the SeV genome, and recombinant infectious SeV mutants with single alanine substitutions at L positions 1782, 1804, 1805, and 1806 or a double substitution at positions 1804 and 1806 were generated. The mutan …
Using a reverse genetics approach, these mutations were introduced into the SeV genome, and recombinant infectious SeV mutants with single a …
11 results