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Year Number of Results
2007 1
2009 1
2012 1
2013 1
2016 1
2017 2
2019 2
2020 1
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2022 3
2023 3
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17 results

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Page 1
The miniature CRISPR-Cas12m effector binds DNA to block transcription.
Wu WY, Mohanraju P, Liao C, Adiego-Pérez B, Creutzburg SCA, Makarova KS, Keessen K, Lindeboom TA, Khan TS, Prinsen S, Joosten R, Yan WX, Migur A, Laffeber C, Scott DA, Lebbink JHG, Koonin EV, Beisel CL, van der Oost J. Wu WY, et al. Among authors: laffeber c. Mol Cell. 2022 Dec 1;82(23):4487-4502.e7. doi: 10.1016/j.molcel.2022.11.003. Epub 2022 Nov 24. Mol Cell. 2022. PMID: 36427491 Free article.
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Omura SN, Nakagawa R, Südfeld C, Villegas Warren R, Wu WY, Hirano H, Laffeber C, Kusakizako T, Kise Y, Lebbink JHG, Itoh Y, van der Oost J, Nureki O. Omura SN, et al. Among authors: laffeber c. Nat Struct Mol Biol. 2023 Aug;30(8):1172-1182. doi: 10.1038/s41594-023-01042-3. Epub 2023 Jul 17. Nat Struct Mol Biol. 2023. PMID: 37460897 Free PMC article.
The selection process of licensing a DNA mismatch for repair.
Fernandez-Leiro R, Bhairosing-Kok D, Kunetsky V, Laffeber C, Winterwerp HH, Groothuizen F, Fish A, Lebbink JHG, Friedhoff P, Sixma TK, Lamers MH. Fernandez-Leiro R, et al. Among authors: laffeber c. Nat Struct Mol Biol. 2021 Apr;28(4):373-381. doi: 10.1038/s41594-021-00577-7. Epub 2021 Apr 5. Nat Struct Mol Biol. 2021. PMID: 33820992
On the Mechanism of Hyperthermia-Induced BRCA2 Protein Degradation.
van den Tempel N, Zelensky AN, Odijk H, Laffeber C, Schmidt CK, Brandsma I, Demmers J, Krawczyk PM, Kanaar R. van den Tempel N, et al. Among authors: laffeber c. Cancers (Basel). 2019 Jan 15;11(1):97. doi: 10.3390/cancers11010097. Cancers (Basel). 2019. PMID: 30650591 Free PMC article.
Tubular and interstitial nephrocalcinosis.
Kummeling MT, de Jong BW, Laffeber C, Kok DJ, Verhagen PC, van Leenders GJ, van Schaik RH, van Woerden CS, Verhulst A, Verkoelen CF. Kummeling MT, et al. Among authors: laffeber c. J Urol. 2007 Sep;178(3 Pt 1):1097-103. doi: 10.1016/j.juro.2007.05.008. Epub 2007 Jul 20. J Urol. 2007. PMID: 17644134
Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
Kaiser FMP, Gruenbacher S, Oyaga MR, Nio E, Jaritz M, Sun Q, van der Zwaag W, Kreidl E, Zopf LM, Dalm VASH, Pel J, Gaiser C, van der Vliet R, Wahl L, Rietman A, Hill L, Leca I, Driessen G, Laffeber C, Brooks A, Katsikis PD, Lebbink JHG, Tachibana K, van der Burg M, De Zeeuw CI, Badura A, Busslinger M. Kaiser FMP, et al. Among authors: laffeber c. J Exp Med. 2022 Sep 5;219(9):e20220498. doi: 10.1084/jem.20220498. Epub 2022 Aug 10. J Exp Med. 2022. PMID: 35947077 Free PMC article.
Correction: Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
Kaiser FMP, Gruenbacher S, Oyaga MR, Nio E, Jaritz M, Sun Q, van der Zwaag W, Kreidl E, Zopf LM, Dalm VASH, Pel J, Gaiser C, van der Vliet R, Wahl L, Rietman A, Hill L, Leca I, Driessen G, Laffeber C, Brooks A, Katsikis PD, Lebbink JHG, Tachibana K, van der Burg M, De Zeeuw CI, Badura A, Busslinger M. Kaiser FMP, et al. Among authors: laffeber c. J Exp Med. 2023 Jan 2;220(1):e2022049812012022c. doi: 10.1084/jem.2022049812012022c. Epub 2022 Dec 7. J Exp Med. 2023. PMID: 36480208 Free PMC article. No abstract available.
Guide-free Cas9 from pathogenic Campylobacter jejuni bacteria causes severe damage to DNA.
Saha C, Mohanraju P, Stubbs A, Dugar G, Hoogstrate Y, Kremers GJ, van Cappellen WA, Horst-Kreft D, Laffeber C, Lebbink JHG, Bruens S, Gaskin D, Beerens D, Klunder M, Joosten R, Demmers JAA, van Gent D, Mouton JW, van der Spek PJ, van der Oost J, van Baarlen P, Louwen R. Saha C, et al. Among authors: laffeber c. Sci Adv. 2020 Jun 17;6(25):eaaz4849. doi: 10.1126/sciadv.aaz4849. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32596446 Free PMC article.
17 results