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High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production.
Heazlewood SY, Ahmad T, Cao B, Cao H, Domingues M, Sun X, Heazlewood CK, Li S, Williams B, Fulton M, White JF, Nebl T, Nefzger CM, Polo JM, Kile BT, Kraus F, Ryan MT, Sun YB, Choong PFM, Ellis SL, Anko ML, Nilsson SK. Heazlewood SY, et al. Among authors: heazlewood ck. Nat Commun. 2023 Apr 13;14(1):2099. doi: 10.1038/s41467-023-37780-7. Nat Commun. 2023. PMID: 37055407 Free PMC article.
Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells.
Sun X, Cao B, Naval-Sanchez M, Pham T, Sun YBY, Williams B, Heazlewood SY, Deshpande N, Li J, Kraus F, Rae J, Nguyen Q, Yari H, Schröder J, Heazlewood CK, Fulton M, Hatwell-Humble J, Das Gupta K, Kapetanovic R, Chen X, Sweet MJ, Parton RG, Ryan MT, Polo JM, Nefzger CM, Nilsson SK. Sun X, et al. Among authors: heazlewood ck. Nat Commun. 2021 May 11;12(1):2665. doi: 10.1038/s41467-021-22863-0. Nat Commun. 2021. PMID: 33976125 Free PMC article.
The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production.
Heazlewood SY, Ahmad T, Mohenska M, Guo BB, Gangatirkar P, Josefsson EC, Ellis SL, Ratnadiwakara M, Cao H, Cao B, Heazlewood CK, Williams B, Fulton M, White JF, Ramialison M, Nilsson SK, Änkö ML. Heazlewood SY, et al. Among authors: heazlewood ck. Blood. 2022 Mar 3;139(9):1359-1373. doi: 10.1182/blood.2021013826. Blood. 2022. PMID: 34852174 Free PMC article.
The role of Tenascin C in the lymphoid progenitor cell niche.
Ellis SL, Heazlewood SY, Williams B, Reitsma AJ, Grassinger J, Borg J, Heazlewood CK, Chidgey AP, Nilsson SK. Ellis SL, et al. Among authors: heazlewood ck. Exp Hematol. 2013 Dec;41(12):1050-61. doi: 10.1016/j.exphem.2013.09.009. Epub 2013 Sep 29. Exp Hematol. 2013. PMID: 24084079 Free article.