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Environmentally-triggered contraction of the norovirus virion determines diarrheagenic potential.
Helm EW, Peiper AM, Phillips M, Williams CG, Sherman MB, Kelley T, Smith HQ, Jacobs SO, Shah D, Tatum SM, Iyer N, Grodzki M, Morales Aparicio JC, Kennedy EA, Manzi MS, Baldridge MT, Smith TJ, Karst SM. Helm EW, et al. Among authors: williams cg. Front Immunol. 2022 Nov 1;13:1043746. doi: 10.3389/fimmu.2022.1043746. eCollection 2022. Front Immunol. 2022. PMID: 36389732 Free PMC article.
Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.
Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, Krogan NJ, Basler CF. Batra J, et al. Among authors: williams cg. EMBO J. 2021 Sep 15;40(18):e105658. doi: 10.15252/embj.2020105658. Epub 2021 Aug 2. EMBO J. 2021. PMID: 34260076 Free PMC article.
Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Among authors: williams cg. Antiviral Res. 2018 Oct;158:288-302. doi: 10.1016/j.antiviral.2018.08.012. Epub 2018 Aug 23. Antiviral Res. 2018. PMID: 30144461 Free PMC article.
Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus.
El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, Parang K. El-Sayed NS, et al. Among authors: williams cg. Eur J Med Chem. 2021 Dec 15;226:113862. doi: 10.1016/j.ejmech.2021.113862. Epub 2021 Sep 21. Eur J Med Chem. 2021. PMID: 34583312 Free PMC article.