Effects of different sources and levels of copper on lipid metabolism in Merino × Texel lambs

Meat Sci. 2019 Sep:155:85-90. doi: 10.1016/j.meatsci.2019.04.021. Epub 2019 Apr 25.

Abstract

The study was conducted with 40 lambs Merino × Texel in order to determine the effects of 10 or 30 mg of Cu/kg DM of copper sulphate and copper-methionine on the lipid and cholesterol metabolism. The lambs were randomly distributed into 5 treatments, with 8 animals each. The treatments were: control, without cooper additions; 10 or 30 mg of Cu/kg DM in the form of copper sulphate; 10 or 30 mg of Cu/kg DM in the form of copper-methionine. The hepatic concentration of copper was higher in lambs supplemented with copper. Total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides in the serum, as well as the SFTU did not differ between treatments. The supplementation of copper regardless of source or level reduced the concentration of cholesterol in the LT muscle, and reduced the concentration of GSH and increased the concentration of GSSG in the liver. Additionally, there was a minimal effect on the fatty acid profile of lipid in lambs.

Keywords: Cholesterol; Fatty acids; Glutathione; Sheep.

MeSH terms

  • Animal Feed / analysis*
  • Animals
  • Cholesterol / blood
  • Copper / analysis
  • Copper Sulfate / administration & dosage
  • Copper Sulfate / pharmacology*
  • Diet / veterinary
  • Fatty Acids / analysis
  • Lipid Metabolism / drug effects*
  • Liver / chemistry
  • Male
  • Methionine / pharmacology*
  • Organometallic Compounds / pharmacology*
  • Random Allocation
  • Sheep, Domestic
  • Triglycerides / blood

Substances

  • Fatty Acids
  • Organometallic Compounds
  • Triglycerides
  • copper methionate
  • Copper
  • Cholesterol
  • Methionine
  • Copper Sulfate