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Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis.
Drapeau E, Mayo W, Aurousseau C, Le Moal M, Piazza PV, Abrous DN. Drapeau E, et al. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14385-90. doi: 10.1073/pnas.2334169100. Epub 2003 Nov 12. Proc Natl Acad Sci U S A. 2003. PMID: 14614143 Free PMC article.
To this end, we took advantage of the existence of spontaneous individual differences observed in aged subjects in a hippocampal-dependent task, the water maze. We expected that the spatial memory capabilities of aged rats would be related to the levels of hippocampal neur …
To this end, we took advantage of the existence of spontaneous individual differences observed in aged subjects in a hippocampal-dependent t …
Neurosteroids: deficient cognitive performance in aged rats depends on low pregnenolone sulfate levels in the hippocampus.
Vallée M, Mayo W, Darnaudéry M, Corpéchot C, Young J, Koehl M, Le Moal M, Baulieu EE, Robel P, Simon H. Vallée M, et al. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14865-70. doi: 10.1073/pnas.94.26.14865. Proc Natl Acad Sci U S A. 1997. PMID: 9405705 Free PMC article.
The spatial memory performances of aged rats were investigated in two different spatial memory tasks, the Morris water maze and Y-maze. Performances in both tests were significantly correlated and, accompanied by appropriate controls, likely evaluated genuine memory …
The spatial memory performances of aged rats were investigated in two different spatial memory tasks, the Morris water maze and Y- …
Efficacy and safety of rucaparib in previously treated, locally advanced or metastatic urothelial carcinoma from a phase 2, open-label trial (ATLAS).
Grivas P, Loriot Y, Morales-Barrera R, Teo MY, Zakharia Y, Feyerabend S, Vogelzang NJ, Grande E, Adra N, Alva A, Necchi A, Rodriguez-Vida A, Gupta S, Josephs DH, Srinivas S, Wride K, Thomas D, Simmons A, Loehr A, Dusek RL, Nepert D, Chowdhury S. Grivas P, et al. BMC Cancer. 2021 May 24;21(1):593. doi: 10.1186/s12885-021-08085-z. BMC Cancer. 2021. PMID: 34030643 Free PMC article. Clinical Trial.
Strain-dependent neurochemical and neuroendocrine effects of desipramine, but not fluoxetine or imipramine, in spontaneously hypertensive and Wistar-Kyoto rats.
Durand M, Aguerre S, Fernandez F, Edno L, Combourieu I, Mormède P, Chaouloff F. Durand M, et al. Neuropharmacology. 2000 Sep;39(12):2464-77. doi: 10.1016/s0028-3908(00)00088-5. Neuropharmacology. 2000. PMID: 10974331
In WKY rats, repeated restraint triggered a desipramine-sensitive 140% increase in hypothalamus [(3)H]nisoxetine binding; moreover, plasma adrenocorticotropin-releasing hormone responses to a 5-min open field test were amplified by prior repeated restraint in both strains, but de …
In WKY rats, repeated restraint triggered a desipramine-sensitive 140% increase in hypothalamus [(3)H]nisoxetine binding; moreover, plasma a …
Identification of female-specific QTLs affecting an emotionality-related behavior in rats.
Ramos A, Moisan MP, Chaouloff F, Mormède C, Mormède P. Ramos A, et al. Mol Psychiatry. 1999 Sep;4(5):453-62. doi: 10.1038/sj.mp.4000546. Mol Psychiatry. 1999. PMID: 10523818
A QTL analysis of the F2 population revealed suggestive loci for various traits, including behaviors in the elevated plus-maze and blood pressure. In addition, one major QTL explaining 50.4% of the total variance (LOD = 7.22) was identified on chromosome 4 for the locomoti …
A QTL analysis of the F2 population revealed suggestive loci for various traits, including behaviors in the elevated plus-maze and bl …
Interleukin-1beta mediates the memory impairment associated with a delayed type hypersensitivity response to bacillus Calmette-Guérin in the rat hippocampus.
Palin K, Bluthé RM, Verrier D, Tridon V, Dantzer R, Lestage J. Palin K, et al. Brain Behav Immun. 2004 May;18(3):223-30. doi: 10.1016/j.bbi.2003.09.002. Brain Behav Immun. 2004. PMID: 15050649
The increase in IL-1beta levels and the decline in IL-1Ra levels were associated with an impairment in spatial memory in a Y-maze on day 16 post-challenge, that was abrogated by chronic administration of IL-1Ra via a subcutaneously implanted osmotic minipump geared to deli …
The increase in IL-1beta levels and the decline in IL-1Ra levels were associated with an impairment in spatial memory in a Y-maze on …