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Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis.
Gelot C, Kovacs MT, Miron S, Mylne E, Haan A, Boeffard-Dosierre L, Ghouil R, Popova T, Dingli F, Loew D, Guirouilh-Barbat J, Del Nery E, Zinn-Justin S, Ceccaldi R. Gelot C, et al. Nature. 2023 Sep;621(7978):415-422. doi: 10.1038/s41586-023-06506-6. Epub 2023 Sep 6. Nature. 2023. PMID: 37674080 Free PMC article.
A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner.
Ragu S, Droin N, Matos-Rodrigues G, Barascu A, Caillat S, Zarkovic G, Siberchicot C, Dardillac E, Gelot C, Guirouilh-Barbat J, Radicella JP, Ishchenko AA, Ravanat JL, Solary E, Lopez BS. Ragu S, et al. Among authors: gelot c. Cell Death Differ. 2023 May;30(5):1349-1365. doi: 10.1038/s41418-023-01141-0. Epub 2023 Mar 3. Cell Death Differ. 2023. PMID: 36869180 Free PMC article.
A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells.
Berrada S, Martínez-Balsalobre E, Larcher L, Azzoni V, Vasquez N, Da Costa M, Abel S, Audoly G, Lee L, Montersino C, Castellano R, Combes S, Gelot C, Ceccaldi R, Guervilly JH, Soulier J, Lachaud C. Berrada S, et al. Among authors: gelot c. Nucleic Acids Res. 2023 Aug 25;51(15):7988-8004. doi: 10.1093/nar/gkad559. Nucleic Acids Res. 2023. PMID: 37395445 Free PMC article.
12 results