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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1950 1
1951 2
1952 1
1957 1
1960 1
1963 2
1966 1
1967 4
1968 1
1969 1
1970 1
1971 2
1972 2
1973 1
1974 1
1976 1
1977 2
1979 4
1980 1
1981 5
1982 1
1983 5
1984 4
1985 2
1986 3
1987 6
1988 6
1989 11
1990 13
1991 14
1992 21
1993 19
1994 20
1995 20
1996 22
1997 23
1998 22
1999 28
2000 37
2001 33
2002 41
2003 47
2004 58
2005 78
2006 81
2007 77
2008 79
2009 73
2010 81
2011 86
2012 82
2013 101
2014 122
2015 135
2016 159
2017 184
2018 155
2019 160
2020 178
2021 219
2022 187
2023 153
2024 49

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2,604 results

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Page 1
Antiviral Profiling of C-18- or C-19-Functionalized Semisynthetic Abietane Diterpenoids.
González-Cardenete MA, Hamulić D, Miquel-Leal FJ, González-Zapata N, Jimenez-Jarava OJ, Brand YM, Restrepo-Mendez LC, Martinez-Gutierrez M, Betancur-Galvis LA, Marín ML. González-Cardenete MA, et al. J Nat Prod. 2022 Aug 26;85(8):2044-2051. doi: 10.1021/acs.jnatprod.2c00464. Epub 2022 Aug 15. J Nat Prod. 2022. PMID: 35969814 Free PMC article. Review.
Several natural and semisynthetic abietane-type diterpenoids have shown important antiviral activities. In this study, a biological evaluation of a number of either C-18- or C-19-functionalized known semisynthetic abietanes against Zika virus, Dengue virus, Herpes v …
Several natural and semisynthetic abietane-type diterpenoids have shown important antiviral activities. In this study, a biological evaluati …
The c-Abl/p73 pathway induces neurodegeneration in a Parkinson's disease model.
Marín T, Valls C, Jerez C, Huerta T, Elgueta D, Vidal RL, Alvarez AR, Cancino GI. Marín T, et al. IBRO Neurosci Rep. 2022 Oct 19;13:378-387. doi: 10.1016/j.ibneur.2022.10.006. eCollection 2022 Dec. IBRO Neurosci Rep. 2022. PMID: 36590096 Free PMC article.
One pro-apoptotic pathway associated with several neurodegenerative diseases is the tyrosine kinase c-Abl and its target p73. Here, we evaluated the contribution of c-Abl and p73 in the degeneration of dopaminergic neurons induced by the neurotoxin 6-hydroxydopamine …
One pro-apoptotic pathway associated with several neurodegenerative diseases is the tyrosine kinase c-Abl and its target p73. Here, w …
c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease.
Marín T, Dulcey AE, Campos F, de la Fuente C, Acuña M, Castro J, Pinto C, Yañez MJ, Cortez C, McGrath DW, Sáez PJ, Gorshkov K, Zheng W, Southall N, Carmo-Fonseca M, Marugán J, Alvarez AR, Zanlungo S. Marín T, et al. Front Cell Dev Biol. 2022 Mar 18;10:844297. doi: 10.3389/fcell.2022.844297. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35399514 Free PMC article.
Interestingly, this kinase is also activated in other lysosomal neurodegenerative disorders. Here, we describe that c-Abl activation contributes to the mechanisms of neuronal damage and death in NPA disease. Our data demonstrate that: 1) c-Abl is activated in-vitro …
Interestingly, this kinase is also activated in other lysosomal neurodegenerative disorders. Here, we describe that c-Abl activation …
Relevant Fusarium Mycotoxins in Malt and Beer.
Pascari X, Marin S, Ramos AJ, Sanchis V. Pascari X, et al. Foods. 2022 Jan 17;11(2):246. doi: 10.3390/foods11020246. Foods. 2022. PMID: 35053978 Free PMC article. Review.
Studies show that germination is the malting step that can lead to a significant increase in the level of all Fusarium mycotoxins. The first step of mashing (45 C) has been proved to possess the most significant impact in the transfer of hydrophilic toxins from the grist i …
Studies show that germination is the malting step that can lead to a significant increase in the level of all Fusarium mycotoxins. The first …
Advances in sepsis biomarkers.
Marin MJ, van Wijk XMR, Chambliss AB. Marin MJ, et al. Adv Clin Chem. 2024;119:117-166. doi: 10.1016/bs.acc.2024.02.003. Epub 2024 Feb 15. Adv Clin Chem. 2024. PMID: 38514209
This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established sepsis biomarkers such lactate, procalcitonin and C-reactive protein, (3) novel, newly regulatory-cleared/approved biomarkers, such as as …
This chapter reviews (1) the basic principles of infectious diseases, pathophysiology and current definition of sepsis, (2) established seps …
GPCR interacting proteins (GIP).
Bockaert J, Fagni L, Dumuis A, Marin P. Bockaert J, et al. Pharmacol Ther. 2004 Sep;103(3):203-21. doi: 10.1016/j.pharmthera.2004.06.004. Pharmacol Ther. 2004. PMID: 15464590 Review.
Other GIPs are soluble proteins interacting mainly with the "magic" C-terminal tail. Among them, PDZ domain-containing proteins are the most abundant. They generally, but not always, interact with the extreme C-terminal domain of GPCRs. Some GIPs interact with speci …
Other GIPs are soluble proteins interacting mainly with the "magic" C-terminal tail. Among them, PDZ domain-containing proteins are t …
The ouabain-insensitive sodium pump.
Proverbio F, Marín R, Proverbio T. Proverbio F, et al. Comp Biochem Physiol A Comp Physiol. 1991;99(3):279-83. doi: 10.1016/0300-9629(91)90002-t. Comp Biochem Physiol A Comp Physiol. 1991. PMID: 1678327 Review. No abstract available.
Review of dementia.
Dugu M, Neugroschl J, Sewell M, Marin D. Dugu M, et al. Mt Sinai J Med. 2003 Jan;70(1):45-53. Mt Sinai J Med. 2003. PMID: 12516009 Review.
It is important to understand the following points: (a). how to diagnose dementia; (b). the etiology of the most common dementias (including Alzheimer s disease, ischemic vascular dementia, and diffuse Lewy body dementia); (c). some medical conditions which could contribut …
It is important to understand the following points: (a). how to diagnose dementia; (b). the etiology of the most common dementias (including …
2,604 results