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Year Number of Results
1975 4
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1985 4
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1998 3
1999 1
2000 8
2001 4
2002 2
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2008 3
2009 3
2010 5
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189 results

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Page 1
Homotropic Cooperativity in Iron-Catalyzed Alkyne Cyclotrimerizations.
Geer AM, Navarro J, Alamán-Valtierra P, Coles NT, Kays DL, Tejel C. Geer AM, et al. ACS Catal. 2023 Apr 28;13(10):6610-6618. doi: 10.1021/acscatal.3c00764. eCollection 2023 May 19. ACS Catal. 2023. PMID: 37229435 Free PMC article.
In addition to the well-established metal-metal and metal-ligand cooperation, we showcase here an example of self-activation by the substrate in controlling the catalytic activity of the two-coordinate iron complex [Fe(2,6-Xyl(2)C(6)H(3))(2)] (1, Xyl = 2,6-Me(2)C …
In addition to the well-established metal-metal and metal-ligand cooperation, we showcase here an example of self-activation by the substrat …
Synthesis and structure-activity relationship of elastase inhibiting novel ethylated thiazole-triazole acetamide hybrids: Mechanistic insights through kinetics and computational contemplations.
Butt ARS, Abbasi MA, Aziz-Ur-Rehman, Siddiqui SZ, Hassan M, Raza H, Shah SAA, Seo SY. Butt ARS, et al. Bioorg Chem. 2019 May;86:197-209. doi: 10.1016/j.bioorg.2019.01.040. Epub 2019 Jan 28. Bioorg Chem. 2019. PMID: 30711702 Review.
The structures of newly synthesized compounds were characterized by (1)H NMR, (13)C NMR, IR and EI-MS spectral studies. The inhibitory effects of these bi-heterocyclic acetamides (9a-n) were evaluated against elastase and all these molecules were identified as poten …
The structures of newly synthesized compounds were characterized by (1)H NMR, (13)C NMR, IR and EI-MS spectral studies. The in …
Synthesis, Kinetics and Computational Explorations of 4-Phenylpiperazine Bearing N-(Aryl)-3-substituted-benzamides as Auspicious Tyrosinase Inhibitors.
Zeb A, Abbasi MA, Aziz-Ur-Rehman, Siddiqui SZ, Hassan M, Javed Q, Rafiq M, Ali A, Shah SAA, Kloczkowski A. Zeb A, et al. Chem Biodivers. 2024 Apr;21(4):e202400133. doi: 10.1002/cbdv.202400133. Epub 2024 Mar 13. Chem Biodivers. 2024. PMID: 38363553
The structures of these newly designed molecules were verified by IR, (1)H-NMR, (13)C-NMR, EI-MS and CHN analysis data. These molecules were screened against tyrosinase and their inhibitory activity explored that these 3-substituted-benzamides exhibit good to excell …
The structures of these newly designed molecules were verified by IR, (1)H-NMR, (13)C-NMR, EI-MS and CHN analysis data. These …
Α-glucosidase inhibitor isolated from coffee.
Kim SD. Kim SD. J Microbiol Biotechnol. 2015 Feb;25(2):174-7. doi: 10.4014/jmb.1411.11057. J Microbiol Biotechnol. 2015. PMID: 25502825 Free article.
The potent alpha-glucosidase inhibitor (compound I) was isolated from coffee brews by the activity-based fractionation and identified as a beta-carboline alkaloid norharman (9H-pyrido[ 3.4-b]indole) on the basis of mass spectroscopy and nuclear magnetic resonance spectra ((1)H …
The potent alpha-glucosidase inhibitor (compound I) was isolated from coffee brews by the activity-based fractionation and identified as a b …
On the limits of complexity in living forms.
Barroso GV, Luz DR. Barroso GV, et al. J Theor Biol. 2015 Aug 21;379:89-90. doi: 10.1016/j.jtbi.2015.04.032. Epub 2015 May 1. J Theor Biol. 2015. PMID: 25939865
In a recent book chapter, Morris, S.C., 2013. Life: the final frontier for complexity? In: Lineweaver, C.H., Davies, P.C.W., Ruse, M. ...
In a recent book chapter, Morris, S.C., 2013. Life: the final frontier for complexity? In: Lineweaver, C.H., Dav …
Mechanistic Insights into the Inhibitory Activities of Chemical Constituents from the Fruits of Terminalia boivinii on α-Glucosidase.
Dlamini BS, Chen CR, Chen YK, Hsu JL, Shih WL, Chang CI. Dlamini BS, et al. Chem Biodivers. 2022 Jul;19(7):e202200137. doi: 10.1002/cbdv.202200137. Epub 2022 Jul 4. Chem Biodivers. 2022. PMID: 35726787
In this study, bioactive constituents were purified from Terminalia boivinii fruits and identified by (1) H-NMR, (13) C-NMR and EI-MS. In vitro and in silico methods were used to evaluate alpha-glucosidase, alpha-amylase, and lipase inhibition activities. ...However …
In this study, bioactive constituents were purified from Terminalia boivinii fruits and identified by (1) H-NMR, (13) C-NMR an …
Biochemical characterization of recombinant Avihepatovirus 3C protease and its localization.
Sun D, Wang M, Wen X, Mao S, Cheng A, Jia R, Yang Q, Wu Y, Zhu D, Chen S, Liu M, Zhao X, Zhang S, Chen X, Liu Y, Yu Y, Zhang L. Sun D, et al. Virol J. 2019 Apr 29;16(1):54. doi: 10.1186/s12985-019-1155-3. Virol J. 2019. PMID: 31036013 Free PMC article.
RESULTS: Under different expression conditions, the 3C protease was found to be highly expressed after induction with 1 mM IPTG at 16 C for 10 h. We synthesized a fluorogenic peptide derived from the cleavage site of the DHAV polyprotein and evaluated the protease a …
RESULTS: Under different expression conditions, the 3C protease was found to be highly expressed after induction with 1 mM IPTG at 16 C …
Preparation, Purification and Characterization of Antibacterial and ACE Inhibitory Peptides from Head Protein Hydrolysate of Kuruma Shrimp, Marsupenaeus japonicus.
Zhou J, Han Q, Koyama T, Ishizaki S. Zhou J, et al. Molecules. 2023 Jan 16;28(2):894. doi: 10.3390/molecules28020894. Molecules. 2023. PMID: 36677951 Free PMC article.
Kuruma shrimp (Marsupenaeus japonicus) heads, as the main by-product of the seafood processing industry, are rich in underutilized high-quality protein. After papain hydrolysis at 50 C for 4 h, the protein hydrolysate of shrimp heads was found to show notable antiba …
Kuruma shrimp (Marsupenaeus japonicus) heads, as the main by-product of the seafood processing industry, are rich in underutilized high-qual …
Angiotensin-I converting enzyme inhibitory peptide derived from the shiitake mushroom (Lentinula edodes).
Paisansak S, Sangtanoo P, Srimongkol P, Saisavoey T, Reamtong O, Choowongkomon K, Karnchanatat A. Paisansak S, et al. J Food Sci Technol. 2021 Jan;58(1):85-97. doi: 10.1007/s13197-020-04517-z. Epub 2020 May 15. J Food Sci Technol. 2021. PMID: 33505054 Free PMC article.
In the results, the optimum condition with the highest DH value of 28.88% was 50.2 C, 3-h hydrolysis time, and 1.16 enzyme/substrate ratios. The highest ACE inhibitory activity (IC(50) of 0.33 mug/mL) was under 47 C, 3 h 28 min hydrolysis time, and 0.5 …
In the results, the optimum condition with the highest DH value of 28.88% was 50.2 C, 3-h hydrolysis time, and 1.16 enzyme/sub …
Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors.
Butt ARS, Abbasi MA, Aziz-Ur-Rehman, Siddiqui SZ, Muhammad S, Raza H, Shah SAA, Shahid M, Alsehemi AG, Kim SJ. Butt ARS, et al. RSC Adv. 2023 May 15;13(20):13798-13808. doi: 10.1039/d3ra01348k. eCollection 2023 May 2. RSC Adv. 2023. PMID: 37197574 Free PMC article.
Considering the varied pharmacological prominence of thiazole and oxadiazole heterocyclic moieties, a unique series of bi-heterocyclic hybrids, 8a-h, was synthesized in a convergent manner. The structures of newly synthesized compounds were characterized by (1)H-NMR …
Considering the varied pharmacological prominence of thiazole and oxadiazole heterocyclic moieties, a unique series of bi-heterocyclic hybri …
189 results