Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 1
1963 2
1964 6
1965 1
1967 1
1968 1
1970 1
1971 1
1975 2
1976 3
1978 1
1980 3
1981 8
1982 11
1983 15
1984 15
1985 11
1986 18
1987 21
1988 30
1989 30
1990 51
1991 101
1992 108
1993 144
1994 158
1995 172
1996 185
1997 210
1998 198
1999 215
2000 245
2001 217
2002 236
2003 267
2004 288
2005 320
2006 316
2007 346
2008 340
2009 355
2010 434
2011 464
2012 487
2013 571
2014 576
2015 582
2016 610
2017 692
2018 711
2019 724
2020 890
2021 915
2022 916
2023 791
2024 242

Text availability

Article attribute

Article type

Publication date

Search Results

12,901 results

Results by year

Filters applied: . Clear all
Page 1
Alternagin-C (ALT-C), a disintegrin-like protein, attenuates alpha2beta1 integrin and VEGF receptor 2 signaling resulting in angiogenesis inhibition.
Dos Santos PK, Altei WF, Danilucci TM, Lino RLB, Pachane BC, Nunes ACC, Selistre-de-Araujo HS. Dos Santos PK, et al. Biochimie. 2020 Jul;174:144-158. doi: 10.1016/j.biochi.2020.04.023. Epub 2020 Apr 30. Biochimie. 2020. PMID: 32360415 Free article.
Furthermore, ALT-C increased the content of the autophagic markers LC3B and Beclin-1 in the presence of VEGF, which is associated with decreased angiogenesis. In conclusion, we suggest that ALT-C, after binding to alpha(2)beta(1) integrin, inhibits VEG …
Furthermore, ALT-C increased the content of the autophagic markers LC3B and Beclin-1 in the presence of VEGF, which is associa …
Low CDK Activity and Enhanced Degradation by APC/C(CDH1) Abolishes CtIP Activity and Alt-EJ in Quiescent Cells.
Li F, Mladenov E, Sun Y, Soni A, Stuschke M, Timmermann B, Iliakis G. Li F, et al. Cells. 2023 Jun 1;12(11):1530. doi: 10.3390/cells12111530. Cells. 2023. PMID: 37296650 Free PMC article.
Alt-EJ is an error-prone DNA double-strand break (DSBs) repair pathway coming to the fore when first-line repair pathways, c-NHEJ and HR, are defective or fail. ...Low levels of CtIP in G(1)-phase cells allow modest resection and alt-EJ, as compared to G(2)-p …
Alt-EJ is an error-prone DNA double-strand break (DSBs) repair pathway coming to the fore when first-line repair pathways, c-N …
Peginterferon alpha-2a (40KD) plus ribavirin: a review of its use in the management of patients with chronic hepatitis C and persistently 'normal' ALT levels.
Keating GM, Plosker GL. Keating GM, et al. Drugs. 2005;65(4):521-36. doi: 10.2165/00003495-200565040-00006. Drugs. 2005. PMID: 15733013 Review.
Combination therapy with subcutaneous peginterferon alpha-2a (40KD) [Pegasys] plus oral ribavirin (Copegus) has been evaluated previously in patients with chronic hepatitis C and elevated ALT levels. A recent randomised, nonblind, multicentre trial examined the effi …
Combination therapy with subcutaneous peginterferon alpha-2a (40KD) [Pegasys] plus oral ribavirin (Copegus) has been evaluated previously in …
Hyperextended telomeres promote formation of C-circle DNA in telomerase positive human cells.
Jones CY, Williams CL, Moreno SP, Morris DK, Mondello C, Karlseder J, Bertuch AA. Jones CY, et al. J Biol Chem. 2023 May;299(5):104665. doi: 10.1016/j.jbc.2023.104665. Epub 2023 Mar 30. J Biol Chem. 2023. PMID: 37003504 Free PMC article.
Up to 15% of cancers utilize a telomerase-independent, recombination-based mechanism termed alternative lengthening of telomeres (ALT). Currently, the primary ALT biomarker is the C-circle, a type of circular DNA with extrachromosomal telomere repeats (cECTRs …
Up to 15% of cancers utilize a telomerase-independent, recombination-based mechanism termed alternative lengthening of telomeres (ALT …
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
Lee J, Lee J, Sohn EJ, Taglialatela A, O'Sullivan RJ, Ciccia A, Min J. Lee J, et al. bioRxiv [Preprint]. 2023 Oct 23:2023.07.31.551186. doi: 10.1101/2023.07.31.551186. bioRxiv. 2023. PMID: 37577643 Free PMC article. Preprint.
A characteristic feature of ALT cancers is the presence of C-circles, circular single-stranded telomeric DNAs composed of C-rich sequences. ...Our work proposes a new model for the generation of C-rich ssDNAs and C-circles during ALT-medi …
A characteristic feature of ALT cancers is the presence of C-circles, circular single-stranded telomeric DNAs composed of C …
[Alanine aminotransferase (ALT)].
Sakagishi Y. Sakagishi Y. Nihon Rinsho. 1995 May;53(5):1146-50. Nihon Rinsho. 1995. PMID: 7602770 Review. Japanese.
Amino acid sequence of c-ALT from rat and human liver has been wholly determined by Ishiguro et al. It is suggested that c-ALT is associated to the utilization of pyruvate in glycolysis and m-ALT is involved in the conversion of alanine to pyruv …
Amino acid sequence of c-ALT from rat and human liver has been wholly determined by Ishiguro et al. It is suggested that c …
The association of ALT to HDL-C ratio with type 2 diabetes in 50-74 years old adults: a population-based study.
Emamian A, Emamian MH, Hashemi H, Fotouhi A. Emamian A, et al. Sci Rep. 2024 Apr 24;14(1):9390. doi: 10.1038/s41598-024-60092-9. Sci Rep. 2024. PMID: 38658745
The mean ALT/HDL-C ratio was reported along with 95% confidence intervals (CI). ...The prevalence of DM was 34.7% and individuals with DM had a mean ALT/HDL-C ratio that was 1.80 units higher than those without diabetes (P < 0.001). ...
The mean ALT/HDL-C ratio was reported along with 95% confidence intervals (CI). ...The prevalence of DM was 34.7% and individu …
The C-Circle Biomarker Is Secreted by Alternative-Lengthening-of-Telomeres Positive Cancer Cells inside Exosomes and Provides a Blood-Based Diagnostic for ALT Activity.
Chen YY, Dagg R, Zhang Y, Lee JHY, Lu R, Martin La Rotta N, Sampl S, Korkut-Demirbaş M, Holzmann K, Lau LMS, Reddel RR, Henson JD. Chen YY, et al. Cancers (Basel). 2021 Oct 26;13(21):5369. doi: 10.3390/cancers13215369. Cancers (Basel). 2021. PMID: 34771533 Free PMC article.
C-Circles, self-primed telomeric C-strand templates for rolling circle amplification, are the only known alternative-lengthening-of-telomeres (ALT)-specific molecule. However, little is known about the biology of C-Circles and if they may be clinically …
C-Circles, self-primed telomeric C-strand templates for rolling circle amplification, are the only known alternative-lengtheni …
Hyperextended telomeres promote C-circle formation in telomerase positive human cells.
Jones CY, Williams CL, Moreno SP, Morris DK, Mondello C, Karlseder J, Bertuch AA. Jones CY, et al. bioRxiv [Preprint]. 2023 Jan 27:2023.01.26.525615. doi: 10.1101/2023.01.26.525615. bioRxiv. 2023. PMID: 36747763 Free PMC article. Updated. Preprint.
Up to 15% of cancers utilize a telomerase-independent, recombination-based mechanism termed alternative lengthening of telomeres (ALT). The primary ALT biomarker is the C-circle, a type of circular DNA with extrachromosomal telomere repeats (cECTRs). ...Addit …
Up to 15% of cancers utilize a telomerase-independent, recombination-based mechanism termed alternative lengthening of telomeres (ALT …
The C-Circle Assay for alternative-lengthening-of-telomeres activity.
Henson JD, Lau LM, Koch S, Martin La Rotta N, Dagg RA, Reddel RR. Henson JD, et al. Methods. 2017 Feb 1;114:74-84. doi: 10.1016/j.ymeth.2016.08.016. Epub 2016 Sep 3. Methods. 2017. PMID: 27595911
The C-Circle Assay has satisfied the need for a rapid, robust and quantitative ALT assay that responds quickly to changes in ALT activity. ...Here we detail the protocols and considerations required to perform the C-Circle Assay and its controls, which …
The C-Circle Assay has satisfied the need for a rapid, robust and quantitative ALT assay that responds quickly to changes in …
12,901 results
You have reached the last available page of results. Please see the User Guide for more information.