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COVID-19 and MIS-C treatment in children-results from an international survey.
Donà D, Minotti C, Masini T, Penazzato M, Van Der Zalm MM, Judd A, Giaquinto C, Lallemant M; Survey Respondents Consortium. Donà D, et al. Eur J Pediatr. 2023 Nov;182(11):5087-5093. doi: 10.1007/s00431-023-05179-7. Epub 2023 Sep 6. Eur J Pediatr. 2023. PMID: 37672062 Free PMC article.
A standardized questionnaire was designed to explore the use of therapeutics used to treat COVID-19 and multisystem inflammatory syndrome in children (MIS-C) in pediatric patients globally. Seventy-three physicians from 29 countries participated. For COVID-19, steroids wer …
A standardized questionnaire was designed to explore the use of therapeutics used to treat COVID-19 and multisystem inflammatory syndrome in …
A physiologic rise in cytoplasmic calcium ion signal increases pannexin1 channel activity via a C-terminus phosphorylation by CaMKII.
López X, Palacios-Prado N, Güiza J, Escamilla R, Fernández P, Vega JL, Rojas M, Marquez-Miranda V, Chamorro E, Cárdenas AM, Maldifassi MC, Martínez AD, Duarte Y, González-Nilo FD, Sáez JC. López X, et al. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2108967118. doi: 10.1073/pnas.2108967118. Proc Natl Acad Sci U S A. 2021. PMID: 34301850 Free PMC article.
Activation of Panx1 has been associated with phosphorylation in a specific tyrosine residue or cleavage of its C-terminal domains. In the present work, we identified a residue (S394) as a putative phosphorylation site by Ca(2+)/calmodulin-dependent kinase II (CaMKII). ...T …
Activation of Panx1 has been associated with phosphorylation in a specific tyrosine residue or cleavage of its C-terminal domains. In …
Global injury morbidity and mortality from 1990 to 2017: results from the Global Burden of Disease Study 2017.
James SL, Castle CD, Dingels ZV, Fox JT, Hamilton EB, Liu Z, S Roberts NL, Sylte DO, Henry NJ, LeGrand KE, Abdelalim A, Abdoli A, Abdollahpour I, Abdulkader RS, Abedi A, Abosetugn AE, Abushouk AI, Adebayo OM, Agudelo-Botero M, Ahmad T, Ahmed R, Ahmed MB, Eddine Aichour MT, Alahdab F, Alamene GM, Alanezi FM, Alebel A, Alema NM, Alghnam SA, Al-Hajj S, Ali BA, Ali S, Alikhani M, Alinia C, Alipour V, Aljunid SM, Almasi-Hashiani A, Almasri NA, Altirkawi K, Abdeldayem Amer YS, Amini S, Loreche Amit AM, Andrei CL, Ansari-Moghaddam A, T Antonio CA, Yaw Appiah SC, Arabloo J, Arab-Zozani M, Arefi Z, Aremu O, Ariani F, Arora A, Asaad M, Asghari B, Awoke N, Ayala Quintanilla BP, Ayano G, Ayanore MA, Azari S, Azarian G, Badawi A, Badiye AD, Bagli E, Baig AA, Bairwa M, Bakhtiari A, Balachandran A, Banach M, Banerjee SK, Banik PC, Banstola A, Barker-Collo SL, Bärnighausen TW, Barrero LH, Barzegar A, Bayati M, Baye BA, Bedi N, Behzadifar M, Bekuma TT, Belete H, Benjet C, Bennett DA, Bensenor IM, Berhe K, Bhardwaj P, Bhat AG, Bhattacharyya K, Bibi S, Bijani A, Bin Sayeed MS, Borges G, Borzì AM, Boufous S, Brazinova A, Briko NI, Budhathoki SS, Car J, Cárdenas R, Carvalho F, Castaldelli-Maia JM, Cas… See abstract for full author list ➔ James SL, et al. Inj Prev. 2020 Oct;26(Supp 1):i96-i114. doi: 10.1136/injuryprev-2019-043494. Epub 2020 Apr 24. Inj Prev. 2020. PMID: 32332142 Free PMC article.
Extending the phenotypes associated with TRIO gene variants in a cohort of 25 patients and review of the literature.
Gazdagh G, Hunt D, Gonzalez AMC, Rodriguez MP, Chaudhry A, Madruga M, Vansenne F, Shears D, Curie A, Stattin EL, Anderlid BM, Trajkova S, Angelovska ES, McWilliam C, Wyatt PR, O'Driscoll M, Atton G, Bergman AK, Zacher P, Mewasingh LD, López AG, Alonso-Luengo O, Wai HA, Rohde O, Boiroux P, Debant A, Schmidt S, Baralle D. Gazdagh G, et al. Am J Med Genet A. 2023 Jul;191(7):1722-1740. doi: 10.1002/ajmg.a.63194. Epub 2023 Mar 29. Am J Med Genet A. 2023. PMID: 36987741 Review.
Here, we report an additional 25, previously unreported individuals who possess heterozygous TRIO variants and we review the literature. In addition, functional studies were performed on the c.4394A > G (N1465S) and c.6244-2A > G TRIO variants to provide evide …
Here, we report an additional 25, previously unreported individuals who possess heterozygous TRIO variants and we review the literature. In …
A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair.
Ruffell D, Mourkioti F, Gambardella A, Kirstetter P, Lopez RG, Rosenthal N, Nerlov C. Ruffell D, et al. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17475-80. doi: 10.1073/pnas.0908641106. Epub 2009 Sep 24. Proc Natl Acad Sci U S A. 2009. PMID: 19805133 Free PMC article.
Conditional deletion of the Cebpb gene in muscle cells does not affect regeneration, showing that the C/EBPbeta cascade leading to muscle repair is muscle-extrinsic. ...
Conditional deletion of the Cebpb gene in muscle cells does not affect regeneration, showing that the C/EBPbeta cascade leading to mu …
Multi-system involvement in a severe variant of fibrodysplasia ossificans progressiva (ACVR1 c.772G>A; R258G): A report of two patients.
Kaplan FS, Kobori JA, Orellana C, Calvo I, Rosello M, Martinez F, Lopez B, Xu M, Pignolo RJ, Shore EM, Groppe JC. Kaplan FS, et al. Am J Med Genet A. 2015 Oct;167A(10):2265-71. doi: 10.1002/ajmg.a.37205. Epub 2015 Jun 11. Am J Med Genet A. 2015. PMID: 26097044 Free PMC article.
One child had sensorineural hearing loss, microcytic anemia, and a tethered spinal cord and the other had a patent ductus arteriosus and gonadal dysgenesis with sex reversal (karyotype 46, XY female). Both children had an identical mutation in ACVR1 c.772A>G; p.Arg258Gl …
One child had sensorineural hearing loss, microcytic anemia, and a tethered spinal cord and the other had a patent ductus arteriosus and gon …
Association of a Blood-Based Aging Biomarker Index With Death and Chronic Disease: Cardiovascular Health Study.
Zhang X, Sanders JL, Boudreau RM, Arnold AM, Justice JN, Espeland MA, Kuchel GA, Barzilai N, Kuller LH, Lopez OL, Kritchevsky SB, Newman AB. Zhang X, et al. J Gerontol A Biol Sci Med Sci. 2024 Feb 1;79(2):glad172. doi: 10.1093/gerona/glad172. J Gerontol A Biol Sci Med Sci. 2024. PMID: 37464278
The BI incorporated circulating levels of new biomarkers, including insulin-like growth factor-1, interleukin-6, amino-terminal pro-B-type natriuretic peptide, cystatin-C, C-reactive protein, tumor necrosis factor-alpha soluble receptor 1, fasting insulin, and fasti …
The BI incorporated circulating levels of new biomarkers, including insulin-like growth factor-1, interleukin-6, amino-terminal pro-B-type n …
Submerged Barriers in the Ni(+) Assisted Decomposition of Propionaldehyde.
Mansell A, Theis Z, Gutierrez MG, Faza ON, Lopez CS, Bellert DJ. Mansell A, et al. J Phys Chem A. 2016 Apr 21;120(15):2275-84. doi: 10.1021/acs.jpca.5b08444. Epub 2016 Apr 7. J Phys Chem A. 2016. PMID: 27054589
The lower energy sequence is a consecutive C-C/C-H addition process with a submerged barrier of 14 350 600 cm(-1). The higher energy sequence is a consecutive C-H/C-C addition process with a submerged barrier of 15 400 600 cm(-1). ...
The lower energy sequence is a consecutive C-C/C-H addition process with a submerged barrier of 14 350 600 cm(-1). The …
117 results